Evidence map›Paper›PMID 39635755›Full record

ArticleBJPsych open2024

Longitudinal changes in cardiac mIBG scintigraphy in mild cognitive impairment with Lewy bodies.

Gemma Greenfinch, Calum A Hamilton, Paul C Donaghy, Michael Firbank, Nicola A Barnett, Louise Allan, George S Petrides, John-Paul Taylor, John T O'Brien, Alan J Thomas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJPsych open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gemma GreenfinchNewcastle University Translational and Clinical Research Institute, Newcastle, UK; The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK; and University College London Hospital, London, UK.ORCID https://orcid.org/0000-0002-6445-4023
Calum A HamiltonNewcastle University Translational and Clinical Research Institute, Newcastle, UK.ORCID https://orcid.org/0000-0002-9812-3150
Paul C DonaghyNewcastle University Translational and Clinical Research Institute, Newcastle, UK.
Michael FirbankNewcastle University Translational and Clinical Research Institute, Newcastle, UK.
Nicola A BarnettNewcastle University Translational and Clinical Research Institute, Newcastle, UK.
Louise AllanUniversity of Exeter Medical School, Exeter, UK.
George S PetridesNuclear Medicine Department, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
John-Paul TaylorNewcastle University Translational and Clinical Research Institute, Newcastle, UK.
John T O'BrienUniversity of Cambridge School of Clinical Medicine, Cambridge, UK.ORCID https://orcid.org/0000-0002-0837-5080
Alan J ThomasNewcastle University Translational and Clinical Research Institute, Newcastle, UK.

Funding

Medical Research Council MR/W000229/1
6 · The paper itself

Abstract

The aim of this study was to determine whether there was a significant change in cardiac [123I]-metaiodobenzylguanidine uptake between baseline and follow-up in individuals with mild cognitive impairment with Lewy bodies (MCI-LB) who had normal baseline scans. Eight participants with a diagnosis of probable MCI-LB and a normal baseline scan consented to a follow-up scan between 2 and 4 years after baseline. All eight repeat scans remained normal; however, in three cases uptake decreased by more than 10%. The mean change in uptake between baseline and repeat was -5.2% (range: -23.8% to +7.0%). The interpolated mean annual change in uptake was -1.6%.

Indexed as

Cardiac mIBGDLBLewy body diseaseMCI-LBsympathetic innervation

Identifiers

PMID39635755
PMCPMC11698149

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.