Evidence map›Paper›PMID 39636514›Full record

ReviewCurrent atherosclerosis reports2024

Statin Use in Children and Adolescents - Dos, Don'ts and Practical Tips.

Don P Wilson, Minali Patel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Don P WilsonDepartments of Pediatric Endocrinology and Diabetes, Cook Children's Medical Center, Fort Worth, TX, USA. don.wilson@cookchildrens.org.
Minali PatelDepartments of Pediatric Endocrinology and Diabetes, Cook Children's Medical Center, Fort Worth, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewWe review treatment criteria in the pediatric population, provide practical advice on how and when to prescribe statins, and share tips to improve compliance. RECENT

findingsAlthough long-term outcome studies of cardiovascular-related events, such as myocardial infarction (MI) and stroke, are lacking in this population, statin therapy initiated during adolescence has been shown to be safe and effective for up to 20 years of continuous use. HMG-CoA reductase inhibitors (statins) are the most effective class of drugs for lowering low-density lipoprotein cholesterol (LDL-C) in children and adolescents.

Indexed as

Hydroxymethylglutaryl-CoA Reductase InhibitorsAdolescentCardiovascular DiseasesChildCholesterol, LDLHumansCholesterol, LDLHydroxymethylglutaryl-CoA Reductase InhibitorsAdolescentsChildrenFamilial hypercholesterolemiaHypercholesterolemiaLipid-lowering medicationStatins

Identifiers

What Socratic holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.