Evidence map›Paper›PMID 39638829›Full record

ArticleScientific reports2024

Prognostic value of the platelet, neutrophil, monocyte, basophil, and eosinophil to lymphocyte ratios in patients with severe community-acquired pneumonia (SCAP).

Xiao-Jiao Cui, Bo Xie, Ke-Wei Zhu, Qian-Qian Liao, Jian-Cheng Zhou, Shan Du, Xin-Xia Liu, Zhu-Jun Chen, Yong Yang, Xiaoqing Yi

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiao-Jiao Cui *Department of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32 West Second Section, 1st Ring Road, Qingyang District, Chengdu, 610072, Sichuan, China.ORCID 0000-0003-1689-0303
Bo Xie *Department of Cardiology, Chengdu First People's Hospital, No.18 North Wanxiang Road, High-tech District, Chengdu, 610016, Sichuan, China.ORCID 0000-0002-9200-9269
Ke-Wei Zhu *Office of Pharmacovigilance, GuangZhou BaiYunShan Pharmaceutical Holdings Co.,Ltd, BaiYunShan Pharmaceutical General Factory, No.88 Yunxiang Road Tonghe Street, Baiyun District, Guangzhou, 510515, Guangdong, China. zhukew2018@outlook.com.ORCID 0000-0002-2138-271X
Qian-Qian LiaoDepartment of Pharmacy, People's Hospital of Guilin, No.12 Civilization Road, Xiangshan District, Guilin, China.
Jian-Cheng ZhouDepartment of Pharmacy, Jiangsu Province Hospital, No.300 Guangzhou Road, Gulou District, Nanjing, China.ORCID 0000-0001-6435-0358
Shan DuDepartment of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32 West Second Section, 1st Ring Road, Qingyang District, Chengdu, 610072, Sichuan, China.ORCID 0000-0002-0031-2667
Xin-Xia LiuDepartment of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32 West Second Section, 1st Ring Road, Qingyang District, Chengdu, 610072, Sichuan, China.ORCID 0000-0002-1640-155X
Zhu-Jun ChenDepartment of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32 West Second Section, 1st Ring Road, Qingyang District, Chengdu, 610072, Sichuan, China.ORCID 0000-0002-6499-9461
Yong YangDepartment of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32 West Second Section, 1st Ring Road, Qingyang District, Chengdu, 610072, Sichuan, China. yyxpower@163.com.ORCID 0000-0001-6747-8592
Xiaoqing YiDepartment of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, No.32 West Second Section, 1st Ring Road, Qingyang District, Chengdu, 610072, Sichuan, China. yixiaoqing198702@126.com.ORCID 0000-0001-6814-3866

Funding

Health Care Commission of Sichuan Province Chuanganyan2023-220
6 · The paper itself

Abstract

Severe community-acquired pneumonia (SCAP) is a serious respiratory inflammation disease with high morbidity and mortality. This study aimed to evaluate the prognostic value of the platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), basophil-to-lymphocyte ratio (BLR) and eosinophil-to-lymphocyte ratio (ELR) in patients with SCAP. The study retrospectively included 554 patients with SCAP, and the clinical data were obtained from the electronic patient record (EMR) system. The primary outcome was in-hospital mortality, and the secondary outcomes included hospital length of stay (LOS), overall survival (OS), admission to ICU, ICU LOS, and ICU mortality. The results showed that both NLR and BLR were significant but not independent prognostic factors for in-hospital mortality; NLR was negatively correlated with hospital LOS while ELR was positively correlated with hospital LOS; both increased NLR and increased BLR were associated with reduced OS, while increased ELR was associated with improved OS; increased PLR, NLR, MLR, and BLR were all correlated with elevated ICU admission rates, while increased ELR was correlated with a reduced ICU admission rate; ELR was positively correlated with ICU LOS; both higher NLR and higher BLR were associated with increased ICU mortality. In summary, NLR and BLR were useful prognostic factors for clinical outcomes in patients with SCAP.

Indexed as

Community-Acquired InfectionsHospital MortalityLymphocytesMonocytesNeutrophilsPneumoniaAgedAged, 80 and overBasophilsBlood PlateletsEosinophilsFemaleHumansIntensive Care UnitsLength of StayLeukocyte CountBasophil-to-lymphocyte ratio (BLR)Eosinophil-to-lymphocyte ratio (ELR)Healthy volunteerMonocyte-to-lymphocyte ratio (MLR)Neutrophil-to-lymphocyte ratio (NLR)Platelet-to-lymphocyte ratio (PLR)

Identifiers

PMID39638829
PMCPMC11621349

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.