Evidence map›Paper›PMID 39638832›Full record

Trial reportScientific reports2024

Comparison of the impact of carotid endarterectomy and stenting on autonomic and baroreflex regulations: a one-year follow-up randomized study.

Vlasta Bari, Giovanni Nano, Irene Baroni, Giada De Angeli, Beatrice Cairo, Francesca Gelpi, Valentina Ceserani, Michele Conti, Francesco Secchi, Alberto Porta and 1 more

Abstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vlasta BariDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Giovanni NanoDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Irene BaroniClinical Research Service, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy. irene.baroni@grupposandonato.it.
Giada De AngeliClinical Research Service, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.
Beatrice CairoDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Francesca GelpiDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Valentina CeseraniDept. of Civil Engineering and Architecture, University of Pavia, Pavia, Italy.
Michele ContiDept. of Civil Engineering and Architecture, University of Pavia, Pavia, Italy.
Francesco SecchiDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Alberto PortaDepartment of Biomedical Sciences for Health, University of Milan, Milan, Italy.
Daniela MazzaccaroOperative Unit of Vascular Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.

Funding

Ministero della Salute PE-2013-02355484
6 · The paper itself

Abstract

Patients with carotid stenosis can receive indication for either carotid endarterectomy (CEA) or carotid artery stenting (CAS), with both techniques having an impact on the autonomic function and baroreflex control.Seventy carotid stenosis patients randomly assigned to CEA or CAS were enrolled. After exclusion of some recordings, 33 CEA (age 67.79 ± 5.32 yrs, 26 males) and 25 CAS (age 70.32 ± 3.63 yrs, 14 males) were admitted to analysis. Autonomic and baroreflex sensitivity markers were derived from the analysis of heart period and systolic arterial pressure spontaneous variability derived in supine position and during active standing (STAND), before (PRE) the intervention and after a 6 and 12-month follow-up (FU6, FU12).CEA had a preserved response of autonomic and baroreflex control to STAND in PRE and FU6, suggesting an early improvement. CAS had a similar response at PRE but a blunted one at the follow-ups. When directly compared, the two groups had a similar autonomic function, with CAS having a reduced baroreflex control in PRE and lower autonomic function at FU6. All the differences disappeared at the long-term follow-up, showing a similar long term effect of the surgical procedures, suggesting that CEA and CAS induced a similar long-term impairment of autonomic and baroreflex controls.

Indexed as

Autonomic Nervous SystemBaroreflexCarotid StenosisEndarterectomy, CarotidStentsAgedBlood PressureFemaleFollow-Up StudiesHeart RateHumansMaleMiddle AgedTreatment OutcomeAutonomic nervous systemBaroreflexCardiovascular riskCarotid artery endarterectomyCarotid artery stentingHeart rate variability

Identifiers

PMID39638832
PMCPMC11621527

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.