Evidence map›Paper›PMID 39638986›Full record

ArticleClinical & experimental ophthalmology

Impact of cataract surgery on patients receiving intravitreal therapy for retinal vein occlusion.

Alessandro Invernizzi, Matteo Airaldi, Mariano Cozzi, Vuong Nguyen, Yohei Hashimoto, Daniel Barthelmes, Louise O'Toole, Theodorus Leonardus Ponsioen, Pavol Kusenda, Francisco Javier Lavid and 3 more

Abstract read
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In one paragraph

Article in Clinical & experimental ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alessandro InvernizziEye Clinic, Department of Biomedical and Clinical Science "Luigi Sacco", Luigi Sacco Hospital, University of Milan, Milan, Italy.ORCID 0000-0003-3400-1987
Matteo AiraldiEye Clinic, Department of Biomedical and Clinical Science "Luigi Sacco", Luigi Sacco Hospital, University of Milan, Milan, Italy.ORCID 0000-0001-9010-1208
Mariano CozziEye Clinic, Department of Biomedical and Clinical Science "Luigi Sacco", Luigi Sacco Hospital, University of Milan, Milan, Italy.ORCID 0000-0001-7777-2461
Vuong NguyenDiscipline of Ophthalmology, Sydney Medical School, The University of Sydney, Save Sight Institute, Sydney, New South Wales, Australia.ORCID 0000-0001-9070-9803
Yohei HashimotoDiscipline of Ophthalmology, Sydney Medical School, The University of Sydney, Save Sight Institute, Sydney, New South Wales, Australia.
Daniel BarthelmesDepartment of Ophthalmology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Louise O'TooleMater Private Hospital, Dublin, Ireland.
Theodorus Leonardus PonsioenDepartment of Ophthalmology, Isala, Zwolle, The Netherlands.
Pavol KusendaDepartment of Ophthalmology, University Hospital-St. Michael's Hospital, Bratislava, Slovakia.
Francisco Javier LavidHospital Punta de Europa, Algeciras, Spain.
Nandor JarossAustralian Eye Specialists, Wyndham & Bacchus Marsh, Werribee, Australia.
Mark GilliesDiscipline of Ophthalmology, Sydney Medical School, The University of Sydney, Save Sight Institute, Sydney, New South Wales, Australia.
Adrian HuntDiscipline of Ophthalmology, Sydney Medical School, The University of Sydney, Save Sight Institute, Sydney, New South Wales, Australia.ORCID 0000-0002-6261-4679

Funding

National Health and Medical Research Council (Australia, NHMRC 2010-1012)Royal Australian and New Zealand College of Ophthalmologists Eye Foundation (Australia, 2007-2009)Unrestricted educational grants from Bayer (Leverkusen, Germany) and Novartis (Basel, Switzerland)
6 · The paper itself

Abstract

backgroundTo assess clinical outcomes of cataract surgery in eyes treated with intravitreal injections for cystoid macular oedema (CMO) secondary to retinal vein occlusions (RVOs).

methodsEyes receiving intravitreal injections for CMO secondary to RVOs that underwent cataract extraction were identified from the Fight Retinal Blindness! Registry and matched 1:1 by 9 parameters with phakic controls also receiving intravitreal injections for the same condition. VA change at 12 months, central subfield thickness (CST) and injection frequency before and after surgery were compared between the two groups. The effect of baseline features on the final VA including age, CST, treatment frequency among others was tested.

resultsWe included 193 eyes that had cataract extraction (exposed) matched with 193 phakic eyes that did not have surgery (matched). VA (95%CI) changed by +9.9 (7, 12.8) letters in exposed eyes versus -2.4 (-4.1, -0.7) letters in matched eyes (p < 0.01). The mean [SD] VA at 12 months was similar in exposed and matched eyes [60.7 (23.0) vs. 61.1 (24.3) letters, respectively, p = 0.81]. The mean [SD] CST was similar between groups before and at surgery, but it was greater in exposed compared with matched eyes [353 (152) vs. 322 (123) μm, respectively, p = 0.03] 12 months after surgery. Exposed eyes received more injections [median (range)] than matched eyes during the 12 months after surgery [5 (3, 7) vs. 4 (1, 6), injections, p < 0.01].

conclusionsCataract extraction delivered good visual outcomes in patients treated for CMO secondary to RVOs. More injections were required on average in the 12 months after surgery in eyes undergoing surgery compared to matched controls.

Indexed as

Angiogenesis InhibitorsCataract ExtractionMacular EdemaPhacoemulsificationRetinal Vein OcclusionAgedAged, 80 and overCataractFemaleGlucocorticoidsHumansIntravitreal InjectionsMaleMiddle AgedRanibizumabRegistriesAngiogenesis InhibitorsGlucocorticoidsRanibizumabVascular Endothelial Growth Factor AVEGFA protein, humananti‐VEGFcataract surgeryoutcomesretinal vein occlusionsRVO

Identifiers

PMID39638986
PMCPMC12129714

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.