Evidence map›Paper›PMID 39640645›Full record

ReviewHeliyon2024

Barley a nutritional powerhouse for gut health and chronic disease defense.

Arif Ali, Zakir Ullah, Rehman Ullah, Mohsin Kazi

RetractedAbstract readReviewRetracted Publication
In one paragraph

Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Arif AliDepartment of Plant Sciences, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, 45320, Pakistan.
Zakir UllahDepartment of Plant Sciences, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, 45320, Pakistan.
Rehman UllahDepartment of Botany, University of Peshawar, Peshawar, 25100, Pakistan.
Mohsin KaziDepartment of Pharmaceutics, College of Pharmacy, POBOX- 2457, King Saud University, Riyadh, 11451, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Digestive issues are recognized as significant contributors to various chronic diseases, including obesity, diabetes, and cardiovascular disease. Barley, a traditional grain, offers considerable promise in addressing these health challenges due to unique nutritional and bioactive compounds. Objective: This review examines the therapeutic potential of various parts of barley, underutilized resource, for chronic disease prevention and management. Method: ology: A comprehensive literature search was conducted across multiple databases like Google Scholar, PubMed, and ISI Web of Science, to identify nutritional components and functional ingredients in barley that contribute to gut health and chronic disease mitigation. Results: The finding suggests that humans digest barley starch more slowly than wheat and rice, which benefits chronic disease management. Barley's high-molecular-weight β-glucan high content acts as a prebiotic, promotes gut health through microbiome modulation and short-chain fatty acid production, potentially preventing colon cancer and boosting immunity. Recent studies on exploring barley grass of high land showed functional ingredients such as flavonoids, saponarin lutonarin, superoxide dismutase, gamma-aminobutyric acid, polyphenols K, Ca, Se, tryptophan chlorophyll, and vitamins, suggesting potential for enhanced antioxidant activity and improved management of chronic conditions like diabetes, cholesterol, hypertension, cardiovascular health, liver protection, and even boosted immunity. Conclusion: This review underscores the therapeutic potential of barley and its components in chronic disease management, highlighting the need for well-designed clinical trials to translate these findings into effective interventions.

Indexed as

Barley grainBarley grassBioactive compoundsChronic diseasesGut healthPhenolic compoundβ-glucan

Identifiers

PMID39640645
PMCPMC11619984

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.