Evidence map›Paper›PMID 39640853›Full record

ArticleFrontiers in microbiology2024

Survey of probable synergism between melittin and ciprofloxacin, rifampicin, and chloramphenicol against multidrug-resistant

Mahsa Sedaghati, Reza Akbari, Lida Lotfollahi Hagghi, Saber Yousefi, Tahere Mesbahi, Mahdieh Delfi

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Antimicrobial Investigation of Phthalimide andLife (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mahsa SedaghatiDepartment of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Reza AkbariDepartment of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Lida Lotfollahi HagghiDepartment of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Saber YousefiDepartment of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Tahere MesbahiDepartment of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Mahdieh DelfiDepartment of Microbiology and Virology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The emergence of multidrug-resistant bacteria and also biofilm-associated infections is a great health concern due to the failure of available antibiotics. This has alerted scientists to developing alternative antibiotics. Melittin as an antimicrobial peptide has antibacterial synergistic activity in combining with conventional antibiotics against pathogenic bacteria. Accordingly, this study aimed to assess the synergistic effect of melittin in combination with Ciprofloxacin, Rifampicin, and Chloramphenicol against MDR strains of Materials and methods: Fifty strains of Results: Out of 50 isolates of Conclusion: Combining melittin's antibacterial and anti-biofilm properties with traditional antibiotics may offer a novel strategy to address antibiotic resistance in

Indexed as

anti-biofilmantimicrobial peptidesmelittinmulti drug resistancesynergism

Identifiers

PMID39640853
PMCPMC11617520

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.