Evidence map›Paper›PMID 39640952›Full record

ArticleObstetric medicine2024

The association of plasma pancreastatin levels with insulin resistance in patients with gestational diabetes mellitus.

Gokcen Unal Kocabas, Ilgin Yildirim Simsir, Banu Sarer Yurekli, Asli Suner Karakulah, Burak Durmaz, Esma Pehlivan Koroglu, Sena Yeral, Busra Ozcan, Ali Akdemir

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obstetric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The role of chromogranin A cleavage products in onset of type 1 and 2 diabetes.Frontiers in clinical diabetes and healthcare · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gokcen Unal KocabasDivision of Endocrinology and Metabolism Disorders, Department of Internal Medicine, Faculty of Medicine, Ege University, Izmir, Turkey.ORCID https://orcid.org/0000-0002-1849-3179
Ilgin Yildirim SimsirDivision of Endocrinology and Metabolism Disorders, Department of Internal Medicine, Faculty of Medicine, Ege University, Izmir, Turkey.ORCID https://orcid.org/0000-0002-6801-8499
Banu Sarer YurekliDivision of Endocrinology and Metabolism Disorders, Department of Internal Medicine, Faculty of Medicine, Ege University, Izmir, Turkey.
Asli Suner KarakulahDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, Ege University, Izmir, Turkey.
Burak DurmazDepartment of Medical Biochemistry, Faculty of Medicine, Ege University, Izmir, Turkey.
Esma Pehlivan KorogluDivision of Endocrinology and Metabolism Disorders, Department of Internal Medicine, Faculty of Medicine, Ege University, Izmir, Turkey.
Sena YeralDivision of Endocrinology and Metabolism Disorders, Department of Internal Medicine, Faculty of Medicine, Ege University, Izmir, Turkey.
Busra OzcanDivision of Endocrinology and Metabolism Disorders, Department of Internal Medicine, Faculty of Medicine, Ege University, Izmir, Turkey.
Ali AkdemirDepartment of Obstetrics and Gynecology, Faculty of Medicine, Ege University, Izmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Gestational diabetes mellitus (GDM) occurs on the background of increased insulin resistance. We aimed to investigate the levels of plasma pancreastatin (PST) levels and its association with metabolic, demographic, and anthropometric parameters in gestational diabetic and normal glucose-tolerant pregnant women. Materials and methods: A total of 165 pregnant women in the 24th-28th week of pregnancy were enrolled in this cross-sectional study. PST levels were measured using ELISA method. Results: Median PST levels were similar between GDM (n = 62, 37.6%) and normal glucose-tolerant control group (n = 103, 62.4%). In the GDM group, PST level showed a significant positive correlation with fasting insulin and the homeostasis model assessment of insulin resistance (HOMA-IR). In binary logistic regression analysis, PST levels did not predict the presence of GDM significantly. Conclusion: Positive correlation of PST with fasting insulin and HOMA-IR suggests that PST could be associated with insulin resistance. Further studies are needed as regards to the role of PST in GDM pathogenesis.

Indexed as

gestational diabetes mellitusinsulin resistancePancreastatin

Identifiers

PMID39640952
PMCPMC11615989

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.