Evidence map›Paper›PMID 39645646›Full record

ArticleJournal of cosmetic dermatology2025

Assessment of Efficacy on the Treatment of Localized Vitiligo With a Combination of 308 nm Excimer Light and 2940 Erbium Laser: A Retrospective Study.

Yihui Xie, Weimin Shi, Wenhao Yin, Xingyu Mei

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yihui XieDepartment of Dermatology, The Affiliated Hospital of Jiaxing University, The First Hospital of Jiaxing, Jiaxing, Zhejiang, China.
Weimin ShiDepartment of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wenhao YinDepartment of Dermatology, The Affiliated Hospital of Jiaxing University, The First Hospital of Jiaxing, Jiaxing, Zhejiang, China.
Xingyu MeiDepartment of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

the Clinical Research Plan of SHDC SHDC22022302the Jiaxing Key Discipline of Medicine-Dermatology and Venereology 2023-FC-006
6 · The paper itself

Abstract

backgroundA 308 nm excimer light is an effective treatment for vitiligo, with fewer treatment times, rapid obvious effects, relatively complete pigment recovery, good patient compliance, and safe and effective treatment for children. The disadvantage of this treatment is that some patients have a plateau during which the skin lesion reduction rate slows down or stalls after multiple treatments.

methodsTreatment data were collected from all vitiligo patients in the Dermatology Department, distinguishing between those who underwent 308 nm excimer light treatment alone and those who received a combination of 308 nm excimer light and 2940 erbium laser treatment.

resultsOf the 104 patients, 60 were treated with 308 nm excimer light only, and 44 were treated with a combination of a 2940 erbium laser and 308 nm excimer light. In contrast to the treatment of 308 nm excimer light alone, the combined treatment of the 2940 erbium laser and 308 nm excimer light significantly increased the speed and degree of repigmentation in vitiligo.

conclusionOur study demonstrates that the combination of 308 nm excimer light and 2940 nm erbium laser treatment can improve the treatment response for vitiligo, decrease the occurrence of treatment plateaus associated with 308 nm excimer light, and improve efficacy.

trial registrationChiCTR2000036712 (24/08/2020).

Indexed as

Lasers, ExcimerLasers, Solid-StateLow-Level Light TherapyVitiligoAdolescentAdultChildCombined Modality TherapyFemaleHumansMaleMiddle AgedRetrospective StudiesSkin PigmentationTreatment OutcomeYoung Adult2940 erbium laser308 nm excimer lightvitiligo

Identifiers

PMID39645646
PMCPMC11845925

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.