ArticleCell reports2024
Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia.
Abstract read
In one paragraph
Article in Cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Crosstalk between vimentin and keratins in viral infection: Implications across the viral life cycle.Virulence · 2026Review
- Immune cell disorder in viral pneumonia.Journal of translational medicine · 2026Review
- Complement Anaphylatoxin C5a-Induced Mouse Lymphatic Functions Modulate Interactions Between Endothelial Cells and T Lymphocytes.Immune network · 2026Article
- Modulating Vimentin: A Systems-Level Therapeutic Strategy for Sepsis and Complex Diseases.Life (Basel, Switzerland) · 2026Article
- The dual role of tissue regulatory T cells in tissue repair: return to homeostasis or fibrosis.Frontiers in immunology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Ruihua MaDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: ruihua.ma@northwestern.edu.
Andrew D PriggeAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Tatiana P Ortiz SerranoDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Yuan ChengDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Jennifer M DavisDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Karen F LouDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Walter A WoodDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Hanh Chi DoDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Ziyou RenDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
McKenzie M FulcerDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Mary J LotestoDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Benjamin D SingerDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Bria M CoatesAnn & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL 60611, USA.
Karen M RidgeDivision of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; Department of Cell and Developmental Biology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: kridge@northwestern.edu.
Funding
Tissue resident macrophages regulate proteostasis in the aging lungP01AG049665 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NAVDEEP S CHANDEL · 2015 to 2026
$26.9MTechnology CoreU19AI135964 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RICHARD G WUNDERINK · 2018 to 2026
$24.7MThe Cell Phenotyping and Mouse CoreP01HL154998 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE · 2021 to 2026
$18.9MTraining Program In Lung SciencesT32HL076139 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE, Jacob I Sznajder · 2004 to 2026
$9.6MThe Neu-Lung Consortium: Neutrophilic Mechanisms of Inflammation, Injury, and Repair in Lung and Airways DiseasesU19AI181102 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Max A Seibold · 2024 to 2026
$9.3MMechanisms of regulatory T cell-mediated recovery from severe viral pneumoniaR01HL149883 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Benjamin David Singer · 2020 to 2026
$4.1MElucidating the role of type I interferon signaling and macrophage-derived inflammation in the juvenile host with viral pneumoniaR01HL168672 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI Bria M Coates · 2023 to 2026
$2.5MElucidating the Role of cGAS-STING in Lung Tissue Repair and RemodelingR01HL166807 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE · 2024 to 2026
$1.8MEpigenetic modifiers of regulatory T cell function following viral pneumoniaR01HL153122 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SINGER, BENJAMIN DAVID · 2021 to 2021
$63kNHLBI NIH HHS P01 HL154998NHLBI NIH HHS R01 HL149883NHLBI NIH HHS R01 HL153122NHLBI NIH HHS R01 HL166807NHLBI NIH HHS R01 HL168672NHLBI NIH HHS T32 HL076139NIAID NIH HHS U19 AI135964NIAID NIH HHS U19 AI181102NIA NIH HHS P01 AG049665
Abstract
Forkhead box P3 (Foxp3)
Indexed as
T-Lymphocytes, RegulatoryVimentinAmphiregulinAnimalsForkhead Transcription FactorsHumansLigandsLungMiceMice, Inbred C57BLPneumonia, ViralReceptors, Antigen, T-CellAmphiregulinForkhead Transcription FactorsLigandsReceptors, Antigen, T-CellVimentinAREGCP: Immunologydistal pole complexepidermal growth factor receptorIL-18Rlung injurylung repairregulatory T cellsTregsvimentinviral pneumonia
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.