Evidence mapPaperPMID 39649015Full record

ArticleGastrointestinal disorders (Basel, Switzerland)2024

Impact of Probiotics and Prebiotics on Gut Microbiome and Hormonal Regulation.

Jelina Basnet, Manar A Eissa, Licy L Yanes Cardozo, Damian G Romero, Samar Rezq

Abstract read
In one paragraph

Article in Gastrointestinal disorders (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jelina BasnetDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Manar A EissaDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Licy L Yanes CardozoDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS 39216, USA.ORCID 0000-0002-7295-1871
Damian G RomeroDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS 39216, USA.ORCID 0000-0002-7268-9690
Samar RezqDepartment of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS 39216, USA.ORCID 0000-0003-4421-0686

Funding

Investigator Development CoreP50MD017338 · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2025 to 2025
$5.9M
Project 003 - Lorena AmaralP20GM121334 · UNIVERSITY OF MISSISSIPPI MED CTR · 2025 to 2025
$2.6M
Pilot Projects ProgramP30GM149404 · UNIVERSITY OF MISSISSIPPI MED CTR · 2025 to 2025
$1.2M
Role of obesity in blood pressure regulation and insulin resistance in Polycystic Ovary SyndromeR01HL171494 · UNIVERSITY OF MISSISSIPPI MED CTR · 2025 to 2025
$668k
NHLBI NIH HHS R01 HL144847NHLBI NIH HHS R01 HL171494NIGMS NIH HHS P20 GM121334NIGMS NIH HHS P30 GM149404NIMHD NIH HHS P50 MD017338
6 · The paper itself

Abstract

The gut microbiome plays a crucial role in human health by influencing various physiological functions through complex interactions with the endocrine system. These interactions involve the production of metabolites, signaling molecules, and direct communication with endocrine cells, which modulate hormone secretion and activity. As a result, the microbiome can exert neuroendocrine effects and contribute to metabolic regulation, adiposity, and appetite control. Additionally, the gut microbiome influences reproductive health by altering levels of sex hormones such as estrogen and testosterone, potentially contributing to conditions like polycystic ovary syndrome (PCOS) and hypogonadism. Given these roles, targeting the gut microbiome offers researchers and clinicians novel opportunities to improve overall health and well-being. Probiotics, such as

Indexed as

dysbiosishormonal disordersprebioticsprobioticssynbiotics

Identifiers

PMID39649015
PMCPMC11623347

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.