Evidence map›Paper›PMID 39651491›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2024

Decoding Dystonia in Autoimmune Disorders: A Scoping Review.

Debayan Dutta, Ravi Yadav

Abstract readScoping Review
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Debayan DuttaDepartment of Neurology, Shalby Hospital, Jabalpur, Madhya Pradesh 48600, India.ORCID 0000-0001-8521-3686
Ravi YadavDepartment of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka 560029, India.ORCID 0000-0002-8016-9089

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dystonia is a common hyperkinetic movement disorder observed in various genetic, infective, drug-induced, and autoimmune disorders. Autoimmune disorders can present with isolated or combined acute or subacute dystonia. The pattern and approach to dystonia in autoimmune disorders are poorly described and have never been established in a structured manner. Objective: This scoping review aims to summarize all available clinical literature and formulate a pattern and approach to dystonia in different autoimmune disorders. Methods: We included one hundred and three articles in this scoping review. Most articles identified were case reports or case series. Results: In this review, we analysed data from 103 articles and summarized the epidemiological, clinical, and diagnostic features of dystonia associated with different autoimmune diseases. We highlight that dystonia can be isolated or combined in various autoimmune conditions and is responsive to immunotherapy. We point out the patterns of dystonia and associated neurological features and investigations that can suggest the underlying autoimmune nature, which can guide the most appropriate treatment. Discussion: The clinical pattern of dystonia can be a unique feature in many autoimmune disorders. In isolated subacute dystonia, the presence of autoantibodies could have a temporal association, or this is just an epiphenomenon to be evaluated in further research. Highlights: Many autoimmune disorders can present with isolated or combined dystonia.Subacute onset focal or segmental dystonia (craniocervical dystonia or limb dystonia) or hemidystonia could be secondary to an autoimmune condition and warrants investigations.They have a relapsing or progressive course.They usually have a good response to early immunotherapy.Symptomatic treatment, including botulinum toxin, can be useful in focal dystonia.

Indexed as

Autoimmune DiseasesDystoniaDystonic DisordersHumansautoimmune dystoniaautoimmune encephalitisdystonia

Identifiers

PMID39651491
PMCPMC11623079

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.