Evidence map›Paper›PMID 39652060›Full record

ArticleJournal of the American Chemical Society2024

Parahydrogen Polarization in Reverse Micelles and Application to Sensing of Protein-Ligand Binding.

Pierce Pham, Oindrila Biswas, Christian Hilty

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The journal of physical chemistry. B · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pierce PhamChemistry Department, Texas A&M University, 3255 TAMU, College Station, Texas 77843, United States.ORCID 0000-0003-3567-4008
Oindrila BiswasChemistry Department, Texas A&M University, 3255 TAMU, College Station, Texas 77843, United States.
Christian HiltyChemistry Department, Texas A&M University, 3255 TAMU, College Station, Texas 77843, United States.ORCID 0000-0003-2539-2568

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A medium containing reverse micelles supports non-hydrogenative parahydrogen induced polarization (nhPHIP) in the organic phase while solubilizing a protein in the aqueous phase. Strongly enhanced NMR signals from iridium hydride complexes report on a ligand, 4-amino-2-benzylaminopyrimidine, which crosses the phase boundary and interacts with the thiaminase protein TenA. The calculation of binding equilibria reveals a

Indexed as

HydrogenMicellesProtein BindingCoordination ComplexesIridiumLigandsPyrimidinesCoordination ComplexesHydrogenIridiumLigandsMicellesPyrimidines

Identifiers

PMID39652060
PMCPMC11664502

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.