Evidence map›Paper›PMID 39652270›Full record

ArticleOdontology2025

Patient-related factors that link chronic kidney disease and periodontitis: a scoping review.

Kübra Kaymaz, Lluís Brunet-Llobet, María Dolores Rocha-Eiroa, Albert Ramírez-Rámiz, Muhiddin Abdi Mahmoud, Elias Isaack Mashala, Jaume Miranda-Rius

Abstract readScoping Review
In one paragraph

Article in Odontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kübra KaymazMaster of Public Health, School of Public Health, Faculty of Medicine, Private Dental Practice, Aberdeen, UK.
Lluís Brunet-LlobetDepartment of Odontostomatology, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.
María Dolores Rocha-EiroaDepartment of Dentistry, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain.
Albert Ramírez-RámizDepartment of Odontostomatology, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.
Muhiddin Abdi MahmoudDepartment of Nephrology and Renal Transplantation, Mnazi Mmoja Referral Hospital, Zanzibar, Tanzania.
Elias Isaack MashalaDoctoral Programme in Medicine and Translational Research, Faculty of Medicine and Health Sciences, Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain.
Jaume Miranda-RiusDepartment of Odontostomatology, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain. jmiranda-rius@ub.edu.ORCID http://orcid.org/0000-0001-8211-1561

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have proposed the existence of an association between periodontitis and chronic kidney disease (CKD) based on biological premises. There is growing evidence that chronic inflammation caused by periodontitis may contribute to the progression of CKD. The present study aimed to investigate studies that link CKD and periodontitis, including periodontitis proxies such as oral hygiene and tooth loss, and patient-related factors such as inflammatory response and genetic polymorphisms. An electronic search was conducted on the MEDLINE (Pubmed), Cochrane Central Register of Controlled Trials (CENTRAL), Scopus, and Web of Science databases using an advanced search option up until August 2024. Thirty-two studies were included: 4 interventional, 16 cohort, and 12 case-control. Overall, the prevalence of periodontitis was significantly higher in patients with CKD: the diagnosis of periodontal disease was associated with an increase in the risk of incident CKD, and parameters of periodontal disease were negatively correlated with kidney function. Inside the field of periodontal medicine, the current evidence indicates a possible association between CKD and periodontitis and supports future longitudinal studies to investigate the two-way relationship between the diseases and their pathophysiology, and possibly to establish cause and effect.

Indexed as

PeriodontitisRenal Insufficiency, ChronicHumansOral HygienePrevalenceRisk FactorsBleeding periodontal pocketsChronic inflammatory diseasesChronic kidney diseaseKidney failurePeriodontitisSubgingival disbiotic biofilmSystemic inflammation

Identifiers

PMID39652270
PMCPMC12178986

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.