Evidence map›Paper›PMID 39652291›Full record

ArticleProbiotics and antimicrobial proteins2025

Evaluating the Impact of Dietary and Water-Based Probiotics on Tilapia Health and Resistance to Aeromonas hydrophila.

Amany M Diab, Fatma Abd El-Rahman, Malik M Khalfallah, Abdallah S Salah, Foad Farrag, Shawky Ibrahim Darwish, Mustafa Shukry

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Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amany M DiabAquatic Microbiology, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, Egypt.
Fatma Abd El-RahmanDepartment of Aquaculture, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.
Malik M KhalfallahDepartment of Aquaculture, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.
Abdallah S SalahDepartment of Aquaculture, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.
Foad FarragDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.
Shawky Ibrahim DarwishDepartment of Limnology, Central Laboratory for Aquaculture Research (CLAR), Abbassa, Sharkia, Egypt.
Mustafa ShukryDepartment of Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt. mostafa.ataa@vet.kfs.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aquaculture plays a critical role in global seafood production. Probiotics in aquaculture have gained popularity for enhancing fish health, growth, and water quality. This study aimed to evaluate the effects of probiotic supplementation through different methods-feed and/or water-on Nile tilapia's growth, health, and resistance to Aeromonas hydrophila. A total of 270 Nile tilapia fingerlings (initial weight 10 ± 05 g) were randomly divided into four experimental groups: (1) control group (basal diet with no probiotics), (2) feed additive group (basal diet + probiotics in feed), (3) water additive group (basal diet + probiotics in water), and (4) combined feed and water additive group (basal diet + probiotics in both feed and water). The trial lasted for 12 weeks. The study assessed water quality, growth performance, feed efficiency, digestive enzyme activities, intestinal morphometry, biochemical and immunological parameters, oxidative status, and resistance to A. hydrophila. The results revealed significant improvements in water quality (reduction in TAN and NH3), growth performance, feed utilization, digestive enzyme activity (amylase, lipase), and immune responses in all probiotic-treated groups compared to the control. The group receiving probiotics in both feed and water showed the highest growth, survival rate, and immune function improvements. Additionally, gene expression analysis revealed upregulation of immune-related cytokines (IL-1β, TGF-β, TNF-α) in this group. In conclusion, administering probiotics via both feed and water significantly enhances Nile tilapia's health, growth, and resistance to bacterial infections, with the combined approach yielding the best results. This study highlights the importance of optimizing probiotic administration methods to maximize benefits in aquaculture systems.

Indexed as

Aeromonas hydrophilaCichlidsFish DiseasesGram-Negative Bacterial InfectionsProbioticsTilapiaAnimal FeedAnimalsAquacultureDietDietary SupplementsDisease ResistanceGrowth performanceImmune responseNile tilapiaProbioticsWater quality

Identifiers

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Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.