Evidence map›Paper›PMID 39652723›Full record

ArticleEuropean thyroid journal2025

Adiposity is associated with a higher number of thyroid nodules and worse fine-needle aspiration outcomes.

Elpida Demetriou, Aliki Economides, Maria Fokou, Demetris Lamnisos, Stavroula A Paschou, Panagiotis Papageorgis, Panayiotis A Economides

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In one paragraph

Article in European thyroid journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elpida DemetriouDepartment of Medicine, School of Medicine, European University Cyprus, Nicosia, Cyprus.
Aliki EconomidesEconomides Thyroid & Endocrinology Center, Nicosia, Cyprus.
Maria FokouDepartment of Medicine, School of Medicine, European University Cyprus, Nicosia, Cyprus.ORCID 0009-0007-3268-6632
Demetris LamnisosDepartment of Life Sciences, European University Cyprus, Nicosia, Cyprus.
Stavroula A PaschouDepartment of Medicine, School of Medicine, European University Cyprus, Nicosia, Cyprus.
Panagiotis PapageorgisDepartment of Life Sciences, European University Cyprus, Nicosia, Cyprus.
Panayiotis A EconomidesDepartment of Medicine, School of Medicine, European University Cyprus, Nicosia, Cyprus.ORCID 0000-0002-5504-5113

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Adiposity may be associated with thyroid nodularity. However, its impact on the number of nodules and the risk of malignancy is unclear. Aim: To evaluate the impact of adiposity on thyroid nodules using body mass index (BMI), ultrasonographic (US) data and cytological data. Methods: A retrospective cohort study of 310 patients with thyroid nodules was performed. Patients were categorized based on their BMI, and grayscale US data and fine-needle aspiration cytology results were evaluated. Results: Patients with BMI ≥ 25 kg/m2 were found to have a higher number of thyroid nodules compared to those with BMI < 25 kg/m2 (4.25 ± 2.42 vs 3.66 ± 1.93) (P value = 0.05). Patients with BMI ≥ 25 kg/m2 had more suspicious and malignant cytology than those with BMI < 25 kg/m2 (P value = 0.029). Patients with BMI ≥ 25 kg/m2 had more nodules with intermediate and high suspicion sonographic patterns. However, this did not reach statistical significance. Conclusion: Overweight and obese patients have a trend for more thyroid nodules and have a higher risk of being diagnosed with thyroid malignancy.

Indexed as

AdiposityBody Mass IndexObesityThyroid NoduleUltrasonographyAdultAgedBiopsy, Fine-NeedleFemaleHumansMaleMiddle AgedOverweightRetrospective StudiesThyroid NeoplasmsadiposityBMIFNAobesitythyroid nodulesthyroid ultrasound

Identifiers

PMID39652723
PMCPMC11816029

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.