Evidence map›Paper›PMID 39653279›Full record

ReviewInternational journal of radiation oncology, biology, physics2025

Dissemination and Implementation-A Primer for Accelerating "Time to Translation" in Radiation Oncology.

Patricia Mae G Santos, Sierra Silverwood, Gita Suneja, Eric C Ford, Nikhil G Thaker, Jamie S Ostroff, Bryan J Weiner, Erin F Gillespie

Abstract readReview
In one paragraph

Review in International journal of radiation oncology, biology, physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Patricia Mae G SantosDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.
Sierra SilverwoodDepartment of Radiation Oncology, University of Washington School of Medicine, Fred Hutch Cancer Center, Seattle, Washington.
Gita SunejaDepartment of Radiation Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.
Eric C FordDepartment of Radiation Oncology, University of Washington School of Medicine, Fred Hutch Cancer Center, Seattle, Washington.
Nikhil G ThakerDepartment of Radiation Oncology, Capital Health, Pennington, New Jersey.
Jamie S OstroffDepartment of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, New York.
Bryan J WeinerDepartment of Global Health, University of Washington School of Medicine, Fred Hutch Cancer Center, Seattle, Washington.
Erin F GillespieDepartment of Radiation Oncology, University of Washington School of Medicine, Fred Hutch Cancer Center, Seattle, Washington. Electronic address: efgillespie@ucsd.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
Leveraging implementation science to accelerate adoption of shorter-course radiation for breast and prostate cancerK08CA252640 · NCI · UNIVERSITY OF WASHINGTON · PI GILLESPIE, ERIN FAYE · 2020 to 2025
$1.3M
Cancer Treatment Disparities in the HIV Population: Exploring the Impact of HIV on Physician and Patient Decision-MakingK08CA228631 · NCI · UNIVERSITY OF UTAH · PI SUNEJA, GITA · 2018 to 2022
$1.2M
NCI NIH HHS K08 CA228631NCI NIH HHS K08 CA252640NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA015704
6 · The paper itself

Abstract

The field of radiation oncology has achieved significant technological and scientific advancements in the 21st century. Yet uptake of new evidence-based practices has been heterogeneous, even in the presence of national and international guidelines. Addressing barriers to practice change requires a deliberate focus on developing and testing strategies tailored to improving care delivery and quality, especially for vulnerable patient populations. Implementation science provides a systematic approach to developing and testing strategies, though applications in radiation oncology remain limited. In this critical review, we aim to (1) assess the time from first evidence to widespread adoption, or "time to translation," across multiple evidence-based practices involving radiation therapy, and (2) provide a primer on the application of implementation science to radiation oncology. Specifically, we discuss potential targets for implementation research in radiation oncology, including both evidence-based practices and quality metrics, and highlight examples of studies evaluating implementation strategies. We also define key concepts and frameworks in the field of implementation science, review common study designs, including hybrid trials and cluster randomization, and discuss the interaction with related disciplines such as quality improvement and behavioral economics. Ultimately, this review aims to illustrate how a comprehensive understanding of implementation science could be used to promote equity and quality in cancer care through the development of effective, scalable, and sustainable care delivery solutions.

Indexed as

Implementation ScienceInformation DisseminationRadiation OncologyTranslational Research, BiomedicalHumansQuality Improvement

Identifiers

PMID39653279
PMCPMC12774429

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.