Evidence map›Paper›PMID 39655256›Full record

ArticleFrontiers in public health2024

The feasibility and impact of deploying a four-tests panel at antenatal care in primary health care facilities of a developing country, Kenya.

Missiani Ochwoto, Micah Matiang'i, Noah Machuki Onchieku, Simon Ndoria, Lydia Matoke, Maureen Otinga, Jeremiah Zablon, Evans Mathebula, Damaris Matoke-Muhia

Abstract read
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Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Missiani OchwotoInnovation Technology Transfer Division, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.
Micah Matiang'iSchool of Medical Sciences, AMREF International University (AMIU), Nairobi, Kenya.
Noah Machuki OnchiekuCentre for Biotechnology Research Development (CBRD), Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.
Simon NdoriaSchool of Medical Sciences, AMREF International University (AMIU), Nairobi, Kenya.
Lydia MatokeCentre for Biotechnology Research Development (CBRD), Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.
Maureen OtingaCentre for Biotechnology Research Development (CBRD), Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.
Jeremiah ZablonLaboratory Medicine and Pathology Department, Brown University, Providence, RI, United States.
Evans MathebulaAbbott Rapid Diagnostics, Abbott, Woodmead, South Africa.
Damaris Matoke-MuhiaCentre for Biotechnology Research Development (CBRD), Kenya Medical Research Institute (KEMRI), Nairobi, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Contracting HIV, syphilis, hepatitis B virus (HBV), and malaria during pregnancy significantly affects the health of the woman, the pregnancy, and the unborn child. The World Health Organization (WHO) recommends testing pregnant women for these infections to achieve triple elimination of mother-to-child transmissions. However, this goal has not been fully realized in low- to medium-income countries, primarily due to segmented testing practices. This study aimed to investigate the effect of introducing a four-tests panel on the quality of antenatal care (ANC) among pregnant women attending selected Primary Health Care facilities in Kenya. Methods: Using a multi-design approach, we analyzed ANC medical records from 577 pregnant women attending eight facilities across four different counties. Blood from the women fingerpick was tested for HIV, Syphilis Hepatitis B Virus and Malaria using the four-tests panel and the results compared to those in the medical records. Results: Out of 577 ANC women, only 8.3% had test results for all four infections available. The majority of the mothers had been tested for syphilis (93.7%), HIV (78.5%), and malaria (62.6%), only 19.5% had been tested for HBV. Testing the women using the 4-tests panel yielded positivity rates of 6.9% for HIV, 0.9% for syphilis, 1.9% for malaria, and 1.1% for HBV. Among those without previous test results, the positivity rate was 2.8% for syphilis, 13.8% for HIV (with 10.6% testing positive for recent p24 infections, F = 24.876, Conclusion: Adopting the 4-tests panel has the potential to improve test result outputs, enhance the quality-of-service delivery, and contribute significantly to the achievement of triple elimination goals.

Indexed as

Developing CountriesHepatitis BHIV InfectionsMalariaPrenatal CarePrimary Health CareSyphilisAdultFeasibility StudiesFemaleHumansInfectious Disease Transmission, VerticalKenyaPregnancyPregnancy Complications, InfectiousYoung Adultantenatal carecongenital syphiliscost benefit analysishepatitis B virus infection (HBV)HIV testP24 antigentest panelstriple elimination

Identifiers

PMID39655256
PMCPMC11626212

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.