Evidence map›Paper›PMID 39655278›Full record

ReviewFrontiers in physiology2024

Signal pathways involved in contrast-induced acute kidney injury.

Ke Deng, Mingxin Pei, Beibei Li, Nanqi Yang, Zijian Wang, Xinchi Wan, Zhiying Zhong, Zhiyi Yang, Yanling Chen

Abstract readReview
In one paragraph

Review in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. High-mobility group box 1 in acute kidney injury.Frontiers in pharmacology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ke DengDepartment of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai, Guangdong, China.
Mingxin PeiDepartment of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai, Guangdong, China.
Beibei LiDepartment of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai, Guangdong, China.
Nanqi YangDepartment of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai, Guangdong, China.
Zijian WangDepartment of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai, Guangdong, China.
Xinchi WanDepartment of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai, Guangdong, China.
Zhiying ZhongDepartment of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai, Guangdong, China.
Zhiyi YangDepartment of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai, Guangdong, China.
Yanling ChenDepartment of Pathophysiology, Zhuhai Campus of Zunyi Medical University, Zhuhai, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contrast-induced acute kidney injury (CI-AKI) has emerged as a global public health concern, ranking as the third most prevalent cause of hospital-acquired acute kidney injury, which is related to adverse outcomes. However, its precise pathogenesis remains elusive. Consequently, researchers are dedicated to uncovering CI-AKI's pathophysiology and signaling pathways, including inflammation, oxidative stress, apoptosis, and ferroptosis, to improve prevention and treatment. This review thoroughly analyzes the signaling pathways and their interactions associated with CI-AKI, assesses the impact of various research models on pathway analysis, and explores more precise targeted treatment and prevention approaches. Aims to furnish a robust theoretical foundation for the molecular mechanisms underpinning clinical treatments.

Indexed as

apoptosiscontrast-induced acute kidney injuryferroptosisinflammationoxidative stresssignal pathways

Identifiers

PMID39655278
PMCPMC11625813

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.