SynthesisEuropean psychiatry : the journal of the Association of European Psychiatrists2024
EPA guidance on lifestyle interventions for adults with severe mental illness: A meta-review of the evidence.
Synthesis in European psychiatry : the journal of the Association of European Psychiatrists, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07446218 (Impact of Pharmacist-Led Interventions in Psychiatric Patients on Second Generation Antipsychotics), which is not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Pharmacist-Led Interventions in Psychiatric Patients on Second Generation Antipsychotics
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Clinical Practice Guideline on the Pharmacological Management of Antipsychotic-Related Dyslipidemia.Schizophrenia bulletin · 2026Guideline
- Guideline
- Short-, Medium-, and Long-Term Cardiometabolic Outcomes in First-Episode Psychosis: A Systematic Review and Meta-analysis.Schizophrenia bulletin · 2026Pooled it
- Trial
- Sedentary Behavior and Physical Activity in Individuals With Bipolar Disorder: An Evidence Synthesis and Position Statement From the ISBD Nutrition and Exercise Task Force (NExT).Bipolar disorders · 2026Review
- Relative risk and risk factors of all-cause, natural-cause and external-cause mortality after psychiatric hospitalisation: a population-based electronic health-record study in Hong Kong.EClinicalMedicine · 2026Article
- Knowledge About Psychosocial Interventions Among Individuals With Severe Mental Illness: Results of a Cross-Sectional Study.Community mental health journal · 2026Article
- Integrating a Physical Therapy Program into Usual Care for Hospital Inpatients with Major Depressive Disorder: Findings from a Case Series.Healthcare (Basel, Switzerland) · 2026Article
- Real-world comprehensive care of people living with schizophrenia: recommendations across different settings and clinical stages.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Mind in motion: patients' experiences with group-based physical activity in psychiatric treatment- a mixed-methods study.BMC psychiatry · 2026Article
- Article
- Emerging Neurobiological and Therapeutic Insights into Schizophrenia: A Comprehensive Review.International journal of molecular sciences · 2026Review
- Bridging the heart-mind divide: Psychiatric implementation of the 2025 ESC mental-CVD consensus.European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- Clinical dietitian-led nutrition counseling and exercise to reduce cardiovascular risk in adults living with a BMI above 27 and severe mental illness: the NORMI-Heart trial protocol.Frontiers in nutrition · 2026Article
- Individual factors associated with physical activity adherence in schizophrenia: an exploratory secondary analysis of two randomized controlled trials.Frontiers in psychology · 2026Article
- Integrating physical healthcare into psychiatry for severe mental illness: A narrative review and position statement from the ECNP PAN-Health group.Neuroscience applied · 2026Review
- Weight gain under antipsychotic and mood stabilizing treatment: a narrative review about mechanisms and future options.International journal of bipolar disorders · 2025Review
- Efficacy of Baduanjin Versus Brisk Walking on Cognitive and Physical Functions in Schizophrenia: A Three-Arm Randomized Controlled Trial.Healthcare (Basel, Switzerland) · 2025Article
- From lifestyle psychiatry to whole person health: Evidence, dissemination, and scalable approaches.European psychiatry : the journal of the Association of European Psychiatrists · 2025Review
- The moderating effect of lifetime physical activity on brain alterations related to adverse childhood experiences.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Funding
Abstract
There is growing interest in lifestyle interventions as stand-alone and add-on therapies in mental health care due to their potential benefits for both physical and mental health outcomes. We evaluated lifestyle interventions focusing on physical activity, diet, and sleep in adults with severe mental illness (SMI) and the evidence for their effectiveness. To this end, we conducted a meta-review and searched major electronic databases for articles published prior to 09/2022 and updated our search in 03/2024. We identified 89 relevant systematic reviews and assessed their quality using the SIGN checklist. Based on the findings of our meta-review and on clinical expertise of the authors, we formulated seven recommendations. In brief, evidence supports the application of lifestyle interventions that combine behavioural change techniques, dietary modification, and physical activity to reduce weight and improve cardiovascular health parameters in adults with SMI. Furthermore, physical activity should be used as an adjunct treatment to improve mental health in adults with SMI, including psychotic symptoms and cognition in adults with schizophrenia or depressive symptoms in adults with major depression. To ameliorate sleep quality, cognitive behavioural informed interventions can be considered. Additionally, we provide an overview of key gaps in the current literature. Future studies should integrate both mental and physical health outcomes to reflect the multi-faceted benefits of lifestyle interventions. Moreover, our meta-review highlighted a relative dearth of evidence relating to interventions in adults with bipolar disorder and to nutritional and sleep interventions. Future research could help establish lifestyle interventions as a core component of mental health care.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.