Evidence map›Paper›PMID 39656238›Full record

ArticleInternational urogynecology journal2025

Effectiveness and Safety Profile of Urethral Bulking with Bulkamid

Gery Lamblin, Solene Boix, Stéphanie Moret, Erdogan Nohuz, Gautier Chene, David Hamid

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International urogynecology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gery LamblinGynecology Surgery Department, Hôpital Femme Mère Enfant, Bron, France. gery.lamblin@chu-lyon.fr.ORCID 0000-0003-3515-8185
Solene BoixGynecology Surgery Department, Hôpital Femme Mère Enfant, Bron, France.
Stéphanie MoretGynecology Surgery Department, Hôpital Femme Mère Enfant, Bron, France.
Erdogan NohuzGynecology Surgery Department, Hôpital Femme Mère Enfant, Bron, France.
Gautier CheneGynecology Surgery Department, Hôpital Femme Mère Enfant, Bron, France.
David HamidClinique Sainte Barbe, Groupe Hospitalier Saint Vincent, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisVarious treatment options are currently available for the management of stress urinary incontinence (SUI). This study was aimed at determining the effectiveness and safety profile of Bulkamid

methodsThis retrospective study conducted in two French urogynecology university centers between September 2019 and December 2023 included all patients with urinary incontinence who received Bulkamid

resultsAmong the 320 patients included (median age 58.2 years), the median follow-up was 24 months. Urethral hypermobility was found in 93.4% of patients (n = 282) and 92% (n = 275) had a positive cough test. At 1 month, 68.7% of patients (n = 220) achieved clinical success, 25.6% (n = 82) improved, and 5.6% (n = 18) reported failure. At last follow-up, 63.7% of patients (n = 204) were still cured, 21.9% (n = 70) had improved, and 14.4% (n = 46) reported failure. Among the 16 patients with overactive bladder (OAB) 43.7% had a Patient Global Improvement (PGI) score of 1-2 at 1 month and 50.0% at last follow-up, with significant difference compared with patients without OAB, 81.0% had a PGI score of 1-2 at 1 month and 74.8% at last follow-up (p = 0.0006 and p = 0.04 respectively). Regarding complications, acute urinary retention occurred in 3.1% of patients (n = 10), urinary infections in 2.2% (n = 7), and transient hematuria in 7.2% (n = 23). In multivariate analysis, follow-up time was significantly associated with failure compared with improvement/cure (OR = 1.05, 95% CI 1.02-1.08, p = 0.0002).

conclusionThe present large series of patients reported the effectiveness of Bulkamid

Indexed as

DimethylpolysiloxanesHyaluronic AcidHydrogelsUrethraUrinary Incontinence, StressAcrylic ResinsAdultAgedCohort StudiesFemaleFranceHumansMiddle AgedRetrospective StudiesTreatment OutcomeAcrylic ResinsBulkamidDimethylpolysiloxanesHyaluronic AcidHydrogelsIntrinsic sphincter deficiencyMid-urethral slingPolyacrylamide hydrogelStress urinary incontinenceTreatment preferenceUrethral bulking agent

Identifiers

PMID39656238

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.