Evidence map›Paper›PMID 39656504›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2025

Myonuclear and satellite cell content of the vastus lateralis and soleus with 70 days of simulated microgravity and the NASA SPRINT exercise program.

Chad M Skiles, Gerard Boyd, Aaron Gouw, Ethan Robbins, Kiril Minchev, Jeffrey Ryder, Lori Ploutz-Snyder, Todd A Trappe, Scott Trappe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chad M SkilesHuman Performance Laboratory, Ball State University, Muncie, Indiana, United States.
Gerard BoydHuman Performance Laboratory, Ball State University, Muncie, Indiana, United States.
Aaron GouwHuman Performance Laboratory, Ball State University, Muncie, Indiana, United States.
Ethan RobbinsHuman Performance Laboratory, Ball State University, Muncie, Indiana, United States.
Kiril MinchevHuman Performance Laboratory, Ball State University, Muncie, Indiana, United States.
Jeffrey RyderUniversities Space Research Association, NASA Johnson Space Center, Houston, Texas, United States.
Lori Ploutz-SnyderUniversities Space Research Association, NASA Johnson Space Center, Houston, Texas, United States.
Todd A TrappeHuman Performance Laboratory, Ball State University, Muncie, Indiana, United States.ORCID 0000-0002-0609-5632
Scott TrappeHuman Performance Laboratory, Ball State University, Muncie, Indiana, United States.ORCID 0000-0002-6438-431X

Funding

HHS | NIH | National Center for Advancing Translational Sciences (NCATS) UL1TR000071National Aeronautics and Space Administration (NASA) NNX11AJ62GNCATS NIH HHS UL1 TR000071
6 · The paper itself

Abstract

We previously observed a range of whole muscle and individual slow and fast myofiber size responses (mean: +4 to -24%) in quadriceps (vastus lateralis) and triceps surae (soleus) muscles of individuals undergoing 70 days of simulated microgravity with or without the NASA SPRINT exercise countermeasures program. The purpose of the current investigation was to further explore, in these same individuals, the content of myonuclei and satellite cells, both of which are key regulators of skeletal muscle mass. Individuals completed 6° head-down-tilt bedrest (BR,

Indexed as

ExerciseQuadriceps MuscleSatellite Cells, Skeletal MuscleWeightlessness SimulationAdultBed RestCell NucleusHead-Down TiltHumansMaleMuscle, SkeletalMyosin Heavy ChainsSpace FlightUnited StatesUnited States National Aeronautics and Space AdministrationMyosin Heavy Chainsbedrestexercisemicrogravitymyonucleisatellite cell

Identifiers

PMID39656504
PMCPMC12188944

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.