Evidence map›Paper›PMID 39656709›Full record

ArticleJournal of occupational and environmental hygiene2025

Application of the Tier 3 NIOSH occupational exposure banding process for the graphene family of nanomaterials: A case study.

Mamadou Niang, Nicole Barcellos, Melissa Edmondson, Lilia Chen, Seth McCormick, Matthew M Dahm

Abstract read
In one paragraph

Article in Journal of occupational and environmental hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mamadou NiangDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio.ORCID 0000-0002-1332-7681
Nicole BarcellosOccupational Health Branch, NASA Glenn Research Center, Cleveland, Ohio.
Melissa EdmondsonDivision of Science Integration, National Institute for Occupational Safety and Health, Cincinnati, Ohio.ORCID 0000-0002-5768-0356
Lilia ChenDivision of Science Integration, National Institute for Occupational Safety and Health, Cincinnati, Ohio.
Seth McCormickDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio.ORCID 0000-0002-4430-6541
Matthew M DahmDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio.ORCID 0000-0001-9770-2700

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Graphene is a class of two-dimensional (2D) nanomaterials composed of single or multiple layers of carbon atoms. To date, there are limited clinical data and no epidemiological research available to assess graphene toxicity in humans. Despite the growing amount of animal toxicity data, there are currently no occupational exposure limits (OELs) for any type of graphene nanomaterial published by international authoritative organizations to ensure their safe handling within workplaces. In the absence of consensus OELs for graphene, the National Institute for Occupational Safety and Health (NIOSH) occupational exposure banding process was used to assign an occupational exposure band (OEB). The NIOSH banding process is organized into a three-tiered system and is a resource for occupational safety and health (OSH) professionals to guide risk management and exposure control decisions when OELs are not available. To the authors' knowledge, there are no Globally Harmonized System of Classification and Labeling of Chemicals (GHS) H-codes/statements available for graphene to conduct a Tier 1 analysis. Even though data were available from authoritative sources for three of nine health endpoints, the data were insufficient to support banding in a Tier 2 assessment. Therefore, a Tier 3 assessment using the NIOSH banding process was applied to the graphene family of nanomaterials (GFN) as a case study based on the specific physicochemical and toxicological properties with uncertainty factor adjustments. The band assignment was replicated by three individuals with advanced toxicology and industrial hygiene knowledge to ensure a consistent outcome. The results found that three of the six endpoints banded were "E," representing an air concentration ≤0.01 mg/m

Indexed as

GraphiteNanostructuresOccupational ExposureAir Pollutants, OccupationalHumansNational Institute for Occupational Safety and Health, U.S.Risk AssessmentUnited StatesAir Pollutants, OccupationalGraphiteHazard evaluationhealth effect endpointsnanomaterialsoccupational exposure banding

Identifiers

PMID39656709
PMCPMC11791868

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.