Evidence map›Paper›PMID 39658737›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Selective PET imaging of CXCR4 using the Al

Muriel Aline Spahn, Tom Van Loy, Sofie Celen, Michel Koole, Christophe M Deroose, Christopher Cawthorne, Wim Vanduffel, Dominique Schols, Guy Bormans, Frederik Cleeren

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Is CXCR4 Theranostics in Oncologic, Cardiovascular, and Inflammatory Diseases Really Happening?Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  2. Article
  3. ComparingCancers · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muriel Aline SpahnRadiopharmaceutical Research, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Tom Van LoyKU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Molecular Structural and Translational Virology Research Group, Leuven, B-3000, Belgium.
Sofie CelenNuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Michel KooleNuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Christophe M DerooseNuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Christopher CawthorneNuclear Medicine and Molecular Imaging, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Wim VanduffelLaboratory for Neuro- and Psychophysiology, KU Leuven Medical School, Leuven, Belgium.
Dominique ScholsKU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Molecular Structural and Translational Virology Research Group, Leuven, B-3000, Belgium.
Guy BormansRadiopharmaceutical Research, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
Frederik CleerenRadiopharmaceutical Research, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium. frederik.cleeren@kuleuven.be.ORCID 0000-0002-3692-1608

Funding

Fonds Wetenschappelijk Onderzoek AKUL15-30/G0H1216NFonds Wetenschappelijk Onderzoek I000321NOnderzoeksraad, KU Leuven C14/21/111Stichting Tegen Kanker C/2020/1528
6 · The paper itself

Abstract

background[

methodsWe designed a CXCR4-specific radioprobe, [

resultsCompared to Ga-PentixaFor, AlF-NOTA-SC demonstrated similar in vitro affinity for human CXCR4. [

conclusion[

Indexed as

Fluorine RadioisotopesPositron-Emission TomographyReceptors, CXCR4AnimalsCell Line, TumorHumansIsotope LabelingMicePeptides, CyclicTissue DistributionCXCR4 protein, humanFluorine-18Fluorine RadioisotopesLY2510924Peptides, CyclicReceptors, CXCR4Al18FAl18F-NOTA-SCCXCR4PET

Identifiers

PMID39658737
PMCPMC11928405

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.