ArticleThe Veterinary record2024
Caregiver-reported increased food motivation and adiposity in dogs receiving antiseizure drugs.
Article in The Veterinary record, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Comparative Neuropharmacological Effects of Antiseizure Drugs on Cultured Myenteric and Dorsal Root Ganglion Neurons.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Behavioural susceptibility to environmental influences in obesity- evidence from a companion animal model.BMC veterinary research · 2026Article
- An olive oil-derived NAE mixture (OlaliamidBMC veterinary research · 2025Article
- Caregiver-reported increased food motivation and adiposity in dogs receiving antiseizure drugs.The Veterinary record · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundIdiopathic epilepsy is the most common chronic neurological disease in dogs and requires lifelong administration of antiseizure drugs (ASD). A decreased level of energy and increased food intake and weight gain have been described as long-lasting side effects.
methodsWe assessed food motivation (FM), using the previously validated dog obesity risk assessment questionnaire, in dogs diagnosed with idiopathic epilepsy (n = 222) and healthy dogs (n = 7086) to determine if epilepsy and ASD were associated with increased FM and adiposity and decreased activity. We also assessed how caregivers managed weight gain in this population of dogs in the study.
resultsDogs with idiopathic epilepsy receiving ASD had significantly higher FM than healthy dogs. Their carers also reported significantly greater interventional effort and food restriction compared with healthy dogs, yet they had significantly higher adiposity. Minimal modelling showed that within the epileptic group, ASD had the highest impact on FM, with an effect size of 32%. LIMITATIONS: Carer-reported data were used, which could have introduced bias. Furthermore, the sample size did not allow us to distinguish the effect of individual ASD.
conclusionsASD increases FM in dogs, resulting in greater adiposity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.