Evidence mapPaperPMID 39659622Full record

ArticleFrontiers in medicine2024

Development and external validation of a prediction model for the risk of relapse in psoriasis after discontinuation of biologics.

Shan Huang, Bailin Chen, Yiming Qi, Xingwu Duan, Yanping Bai

Abstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shan Huang *Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Bailin Chen *Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Yiming QiGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Xingwu DuanDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yanping BaiDepartment of Dermatology, China-Japan Friendship Hospital, National Center for Integrative Chinese and Western Medicine, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Some patients with psoriasis experience relapses shortly after discontinuation of biologics. However, there is a lack of risk prediction tools to identify those at high risk of relapse. Objective: To develop and validate a risk prediction model for psoriasis relapse after biologics discontinuation. Methods: Publications from PubMed, EMBASE, Medline, and the Cochrane Library were systematically searched and meta-analyses were conducted to identify risk factors for psoriasis relapse after biologics discontinuation. Statistically significant risk factors were identified and used to create a risk assessment model weighted by the impact of each factor. The model was externally validated using a cohort of 416 Chinese psoriasis patients. Results: Eight studies ( Conclusion: Multivariate models using available clinical parameters can predict relapse risk in psoriasis patients after biologics discontinuation. Early individual identification of patients at risk of relapse, and screening of candidate cohorts for long-term treatment or dose reduction may benefit both patients and physicians.

Indexed as

biologicsprediction modelpsoriasisrelapserisk factor

Identifiers

PMID39659622
PMCPMC11628277

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.