Evidence map›Paper›PMID 39659942›Full record

ReviewAmerican journal of cancer research2024

The role of novel adipokines in hepatocellular carcinoma progression: a mini review.

Panpan Hu, Dezhi Guo, Keyun Cao, Tianying Xu

Abstract readReview
In one paragraph

Review in American journal of cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Panpan HuDepartment of Anesthetic Pharmacology, School of Anesthesiology, Second Military Medical University/Naval Medical University Shanghai 200433, China.
Dezhi GuoDepartment of Anesthetic Pharmacology, School of Anesthesiology, Second Military Medical University/Naval Medical University Shanghai 200433, China.
Keyun CaoDepartment of Anesthetic Pharmacology, School of Anesthesiology, Second Military Medical University/Naval Medical University Shanghai 200433, China.
Tianying XuDepartment of Anesthetic Pharmacology, School of Anesthesiology, Second Military Medical University/Naval Medical University Shanghai 200433, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC), which originates from hepatocytes, accounts for the majority of primary liver cancers. Globally, HCC ranks among the most common cancers and is a leading cause of cancer-related deaths. Obesity, a growing health issue worldwide, is increasingly recognized as a critical risk factor for HCC, influenced by both epidemiological and clinical factors. Adipokines, secreted by adipocytes, have been shown to play pivotal roles in the tumor microenvironment, affecting cancer progression, metastasis, and resistance to therapies through various signaling mechanisms. Despite inconsistencies in certain findings, a substantial body of research supports the significant role of adipokines in HCC development. This review focuses on exploring newly identified adipokines and their mechanisms in HCC, with the goal of uncovering potential therapeutic targets for improved management and treatment strategies.

Indexed as

Adipokineshepatocellular carcinomaprognosistumorigenesis

Identifiers

PMID39659942
PMCPMC11626281

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.