Evidence map›Paper›PMID 39660854›Full record

ArticleAnalytical chemistry2024

Imaging G-Quadruplex Nucleic Acids in Live Cells Using Thioflavin T and Fluorescence Lifetime Imaging Microscopy.

Tigerlily Bradford, Peter A Summers, Aatikah Majid, Petr S Sherin, Jeff Yui Long Lam, Savyasanchi Aggarwal, Jean-Baptiste Vannier, Ramon Vilar, Marina K Kuimova

Abstract read
In one paragraph

Article in Analytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tigerlily BradfordMolecular Sciences Research Hub, Department of Chemistry, Imperial College London, London W12 0BZ, U.K.
Peter A SummersMolecular Sciences Research Hub, Department of Chemistry, Imperial College London, London W12 0BZ, U.K.ORCID 0000-0001-5538-525X
Aatikah MajidMolecular Sciences Research Hub, Department of Chemistry, Imperial College London, London W12 0BZ, U.K.
Petr S SherinMolecular Sciences Research Hub, Department of Chemistry, Imperial College London, London W12 0BZ, U.K.ORCID 0000-0002-9169-4655
Jeff Yui Long LamMolecular Sciences Research Hub, Department of Chemistry, Imperial College London, London W12 0BZ, U.K.
Savyasanchi AggarwalMolecular Sciences Research Hub, Department of Chemistry, Imperial College London, London W12 0BZ, U.K.ORCID 0009-0007-7128-3465
Jean-Baptiste VannierTelomere Replication and Stability Group, MRC London Institute of Medical Sciences, London W12 0NN, U.K.
Ramon VilarMolecular Sciences Research Hub, Department of Chemistry, Imperial College London, London W12 0BZ, U.K.ORCID 0000-0003-2992-199X
Marina K KuimovaMolecular Sciences Research Hub, Department of Chemistry, Imperial College London, London W12 0BZ, U.K.ORCID 0000-0003-2383-6014

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visualization of guanine-rich oligonucleotides that fold into G-quadruplex (G4) helical structures is of great interest in cell biology. There is a large body of evidence that suggests that these noncanonical structures form

Indexed as

BenzothiazolesFluorescent DyesG-QuadruplexesMicroscopy, FluorescenceCell Line, TumorDNAHumansOptical ImagingQuinolinesThiazolesBenzothiazolesDNAFluorescent DyesQuinolinesthiazole orangeThiazolesthioflavin T

Identifiers

PMID39660854
PMCPMC11672229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.