ArticleThe European journal of neuroscience2025
Daily rhythms drive dynamism in sleep, oscillations and interneuron firing, while excitatory firing remains stable across 24 h.
Article in The European journal of neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Circadian gatekeepers of the gut-brain-immune axis: implications for neuroinflammation and neurodegeneration.Journal of neuroinflammation · 2026Review
- Daytime lighting conditions alter home-cage behavior across both sexes in diurnal grass rats.Frontiers in neuroscience · 2026Article
- Daily rhythms drive dynamism in sleep, oscillations and interneuron firing, while excitatory firing remains stable across 24 h.The European journal of neuroscience · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The adaptation to the daily 24-h light-dark cycle is ubiquitous across animal species and is crucial for maintaining fitness. This free-running cycle occurs innately within multiple bodily systems, such as endogenous circadian rhythms in clock-gene expression and synaptic plasticity. These phenomena are well studied; however, it is unknown if and how the 24-h clock affects electrophysiologic network function in vivo. The hippocampus is a region of interest for long timescale (>8 h) studies because it is critical for cognitive function and exhibits time-of-day effects in learning. We recorded single cell spiking activity and local field potentials (LFPs) in mouse hippocampus across the 24-h (12:12-h light/dark) cycle to quantify how electrophysiological network function is modulated across the 24-h day. We found that while inhibitory population firing rates and LFP oscillations exhibit modulation across the day, average excitatory population firing is static. This excitatory stability, despite inhibitory dynamism, may enable consistent around-the-clock function of neural circuits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.