Evidence map›Paper›PMID 39663299›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2025

Association of Parity with Type 2 Diabetes Mellitus in Japan.

Hongxin Wang, Noriyuki Iwama, Keiichi Yuwaki, You Nakamichi, Hirotaka Hamada, Hasumi Tomita, Kazuma Tagami, Rie Kudo, Natsumi Kumagai, Hirohito Metoki and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hongxin WangDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, Japan.
Noriyuki IwamaDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, Japan. noriyuki.iwama.a3@tohoku.ac.jp.ORCID 0000-0002-6808-0911
Keiichi YuwakiUnderwriting and Medical Department, The Dai-Ichi Life Insurance Company, Limited, 3-2-3, Toyosu, Koto-Ku, Tokyo, Japan.
You NakamichiUnderwriting and Medical Department, The Dai-Ichi Life Insurance Company, Limited, 3-2-3, Toyosu, Koto-Ku, Tokyo, Japan.
Hirotaka HamadaDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, Japan.
Hasumi TomitaDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, Japan.
Kazuma TagamiDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, Japan.
Rie KudoDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, Japan.
Natsumi KumagaiDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, Japan.
Hirohito MetokiTohoku Medical Megabank Organization, Tohoku University, 2-1, Seiryomachi, Sendai, Miyagi, Japan.
Naoki NakayaTohoku Medical Megabank Organization, Tohoku University, 2-1, Seiryomachi, Sendai, Miyagi, Japan.
Atsushi HozawaTohoku Medical Megabank Organization, Tohoku University, 2-1, Seiryomachi, Sendai, Miyagi, Japan.
Shinichi KuriyamaDivision of Molecular Epidemiology, Tohoku University Graduate School of Medicine, 1-1, Seiryomachi, Sendai, Miyagi, Japan.
Nobuo YaegashiDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, Japan.
Masatoshi SaitoDepartment of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Tohoku University Hospital, 1-1, Seiryomachi, Sendai, Miyagi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the association between parity and type 2 diabetes mellitus (T2DM) in Japanese women, considering the clinical history of gestational diabetes mellitus (GDM) and menopausal status, which are known risk factors for T2DM. Overall, 30,116 Japanese women (6,588 premenopausal and 23,528 postmenopausal) were included in this cross-sectional study. They were divided into two groups according to menopausal status (premenopausal and postmenopausal women), and the association between parity and T2DM was evaluated using a multiple logistic regression model with possible confounders, including a clinical history of GDM. The association between parity and T2DM was not statistically significant in premenopausal women. In contrast, a linear graded association between parity and T2DM was found in postmenopausal women. Furthermore, the association between parity and T2DM in postmenopausal women was attenuated after adjusting for body weight gain after the age of 20 years. A clinical history of GDM was significantly associated with a high risk for T2DM, regardless of adjustment for body weight gain after the age of 20 years in both premenopausal and postmenopausal women. Parity is associated with an increased risk of T2DM in postmenopausal women but not in premenopausal women. Maintaining appropriate body weight would be beneficial in attenuating the risk of T2DM in postmenopausal women. A clinical history of GDM is a risk factor for T2DM in both pre- and postmenopausal women; therefore, women with a clinical history of GDM require continuous medical care to survey for T2DM.

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 2ParityAdultAgedCross-Sectional StudiesFemaleHumansJapanMiddle AgedPostmenopausePregnancyPremenopauseRisk FactorsCohort studyDiabetes mellitusGestational diabetes mellitusParity

Identifiers

PMID39663299
PMCPMC11825537

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.