Evidence map›Paper›PMID 39664449›Full record

ArticleFrontiers in neuroscience2024

Drug-induced parkinsonism in a patient with DiGeorge syndrome: a case report.

Clancy Cerejo, Nicolas De Cleene, Gerald Walser, Atbin Djamshidian, Klaus Seppi, Beatrice Heim

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In one paragraph

Article in Frontiers in neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Clancy CerejoDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Nicolas De CleeneDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Gerald WalserDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Atbin DjamshidianDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Klaus SeppiDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Beatrice HeimDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DiGeorge syndrome, also referred as 22q11.2 deletion syndrome is a multisystem disorder associated with an increased risk of early-onset parkinsonism. In this case report, we present a case of a 47-year-old male patient with complex comorbidities and seizures. This patient presented with increased seizure frequency and on examination was found to have parkinsonism. Due to the symptoms constellation, a genetic analysis was done which revealed presence of DiGeorge syndrome. However, his DaTscan was normal and hence a possibility of medication induced parkinsonism was considered. Through this case report, we want to emphasize the fact that while it is important to consider genetic testing for young patients with parkinsonism especially in those with complex comorbidities, other possible causes of parkinsonism should not be ignored.

Indexed as

DiGeorge syndromedrug inducedearly-onsetlamotrigineparkinsonism

Identifiers

PMID39664449
PMCPMC11631938

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.