Evidence map›Paper›PMID 39664495›Full record

ArticleFrontiers in cellular and infection microbiology2024

Multiple factors regulate the expression of

Kassapa Ellepola, Lauren C Guillot, Bradley Comeaux, Yiran Han, Jessica K Kajfasz, Jacob P Bitoun, Grace Spatafora, Jose A Lemos, Zezhang T Wen

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. An XRE-type regulator inMicrobiology spectrum · 2026
    Article
  2. SppR inFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kassapa EllepolaDepartment of Oral and Craniofacial Biology, School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Lauren C GuillotDepartment of Oral and Craniofacial Biology, School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Bradley ComeauxDepartment of Oral and Craniofacial Biology, School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Yiran HanDepartment of Biology, Middlebury College, Middlebury, VT, United States.
Jessica K KajfaszDepartment of Oral Biology, School of Dentistry, University of Florida, Gainesville, FL, United States.
Jacob P BitounDepartment of Microbiology, Tulane University, New Orleans, LA, United States.
Grace SpataforaDepartment of Biology, Middlebury College, Middlebury, VT, United States.
Jose A LemosDepartment of Oral Biology, School of Dentistry, University of Florida, Gainesville, FL, United States.
Zezhang T WenDepartment of Oral and Craniofacial Biology, School of Dentistry, Louisiana State University Health Sciences Center, New Orleans, LA, United States.

Funding

BrpA in Virulence Modulation of Streptococcus mutansR01DE019452 · NIDCR · LSU HEALTH SCIENCES CENTER · PI ZEZHANG TOM WEN, Hui Wu · 2009 to 2026
$6.3M
Investigating SloR virulence gene metalloregulation in Streptococcus mutansR01DE014711 · NIDCR · MIDDLEBURY COLLEGE · PI SPATAFORA, GRACE A. · 2004 to 2021
$4.1M
More Than Mechanical Retention: Characterization of Lactobacillus Clinical Strains Using In Vitro ModelsR21DE031856 · NIDCR · LSU HEALTH SCIENCES CENTER · PI WEN, ZEZHANG TOM · 2023 to 2024
$444k
NIDCR NIH HHS R01 DE014711NIDCR NIH HHS R01 DE019452NIDCR NIH HHS R21 DE031856
6 · The paper itself

Abstract

Introduction: The Methods: In this study, luciferase reporter fusion assays, electrophoretic gel mobility shift assays (EMSA) and Results and discussion: Results showed deletion of

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialPromoter Regions, GeneticStreptococcus mutansElectrophoretic Mobility Shift AssayGene DeletionGenes, ReporterIronIron-Sulfur ProteinsLuciferasesMultigene FamilyMutagenesis, Site-DirectedProtein BindingTranscription FactorsTranscription, GeneticBacterial ProteinsIronIron-Sulfur ProteinsLuciferasesTranscription FactorsCysRDprgene expressionPerRSloRSpxAStreptococcus mutanssufCDSUB

Identifiers

PMID39664495
PMCPMC11631912

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.