Evidence mapPaperPMID 39664998Full record

ReviewArchives of endocrinology and metabolism2024

Pharmacologic Treatment of Obesity in adults and its impact on comorbidities: 2024 Update and Position Statement of Specialists from the Brazilian Association for the Study of Obesity and Metabolic Syndrome (Abeso) and the Brazilian Society of Endocrinology and Metabolism (SBEM).

Rodrigo O Moreira, Cynthia M Valerio, Alexandre Hohl, Cristiane Moulin, Fábio Moura, Fábio R Trujilho, Fernando Gerchman, Livia L Correa, Marcio C Mancini, Maria Edna Melo and 5 more

Abstract readReviewConsensus Statement
In one paragraph

Review in Archives of endocrinology and metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Rodrigo O MoreiraInstituto Estadual de Diabetes e Endocrinologia Luis Capriglione Rio de JaneiroRJ Brasil Instituto Estadual de Diabetes e Endocrinologia Luis Capriglione, Rio de Janeiro, RJ, Brasil.ORCID https://orcid.org/0000-0003-1561-2926
Cynthia M ValerioInstituto Estadual de Diabetes e Endocrinologia Luis Capriglione Rio de JaneiroRJ Brasil Instituto Estadual de Diabetes e Endocrinologia Luis Capriglione, Rio de Janeiro, RJ, Brasil.ORCID https://orcid.org/0000-0003-2292-1735
Alexandre HohlDepartamento de Clínica Médica Universidade Federal de Santa Catarina FlorianópolisSC Brasil Departamento de Clínica Médica, Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.ORCID https://orcid.org/0000-0002-8073-5837
Cristiane MoulinCentro Especializado em Diabetes, Obesidade e Hipertensão Secretaria de Saúde do Distrito Federal BrasíliaDF Brasil Centro Especializado em Diabetes, Obesidade e Hipertensão, Secretaria de Saúde do Distrito Federal, Brasília, DF, Brasil.ORCID https://orcid.org/0009-0006-7213-2418
Fábio MouraUniversidade de Pernambuco RecifePE Brasil Universidade de Pernambuco, Recife, PE, Brasil.ORCID https://orcid.org/0000-0001-6721-6437
Fábio R TrujilhoCentro de Diabetes e Endocrinologia da Bahia SalvadorBA Brasil Serviço de Obesidade e Lipodistrofia, Centro de Diabetes e Endocrinologia da Bahia, Salvador, BA, Brasil.ORCID https://orcid.org/0009-0000-1987-8348
Fernando GerchmanDepartamento de Clínica Médica Faculdade de Medicina Universidade Federal do Rio Grande do Sul Porto AlegreRS Brasil Departamento de Clínica Médica, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.ORCID https://orcid.org/0000-0001-5873-9498
Livia L CorreaInstituto Estadual de Diabetes e Endocrinologia Luis Capriglione Rio de JaneiroRJ Brasil Instituto Estadual de Diabetes e Endocrinologia Luis Capriglione, Rio de Janeiro, RJ, Brasil.ORCID https://orcid.org/0000-0003-4656-4381
Marcio C ManciniHospital das Clínicas Faculdade de Medicina Universidade de São Paulo São PauloSP Brasil Grupo de Obesidade, Disciplina de Endocrinologia e Metabolismo, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.ORCID https://orcid.org/0000-0003-1278-0406
Maria Edna MeloHospital das Clínicas Faculdade de Medicina Universidade de São Paulo São PauloSP Brasil Grupo de Obesidade, Disciplina de Endocrinologia e Metabolismo, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.ORCID https://orcid.org/0000-0002-1216-7532
Rodrigo N LamounierDepartamento de Clínica Médica Universidade Federal de Minas Gerais Belo HorizonteMG Brasil Departamento de Clínica Médica, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.ORCID https://orcid.org/0000-0001-7432-9085
Simone van de Sande-LeeDepartamento de Clínica Médica Universidade Federal de Santa Catarina FlorianópolisSC Brasil Departamento de Clínica Médica, Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.ORCID https://orcid.org/0000-0002-5592-1603
Thaísa D G TrujilhoCentro de Diabetes e Endocrinologia da Bahia SalvadorBA Brasil Serviço de Obesidade e Lipodistrofia, Centro de Diabetes e Endocrinologia da Bahia, Salvador, BA, Brasil.ORCID https://orcid.org/0000-0001-5162-1905
Paulo A C MirandaHospital Mater Dei Belo HorizonteMG Brasil Serviço de Endocrinologia, Hospital Mater Dei, Belo Horizonte, MG, Brasil.ORCID https://orcid.org/0000-0001-5433-3386
Bruno HalpernCentro de Obesidade Hospital Nove de Julho São PauloSP Brasil Centro de Obesidade, Hospital Nove de Julho, São Paulo, SP, Brasil.ORCID https://orcid.org/0000-0003-0973-5065

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmacological treatment of obesity is passing through many changes in the last decades; different agents have been approved, and newer options are leaning towards higher efficacy and a more favourable safety profile; however, medications approved for a longer time are still available and useful for many patients. This document is an 2024 Update Position Statement of Specialists from the Brazilian Association for the Study of Obesity and Metabolic Syndrome (Abeso) and the Brazilian Society of Endocrinology and Metabolism (SBEM), with the aim of reviewing all the approved medications for the management of obesity in Brazil (sibutramine, orlistat, liraglutide, semaglutide and bupropion/naltrexone fixed dose), with the addition of tirzepatide, that is approved in other countries and likely approved soon in Brazil. The review is focused on efficacy, safety profile and the impact of drugs (based on existing studies) on different comorbidities.

Indexed as

Anti-Obesity AgentsComorbidityMetabolic SyndromeObesitySocieties, MedicalAdultBrazilEndocrinologyHumansAnti-Obesity Agentsantiobesity drugsObesityweight loss

Identifiers

PMID39664998
PMCPMC11634287

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.