ArticleJournal of the National Cancer Institute2025
Time-restricted eating and cancer: lessons learned and considerations for a path forward.
Article in Journal of the National Cancer Institute, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The Interplay Between Circadian Clocks and the Tumour Microenvironment in Breast Cancer.Cancers · 2026Review
- Intermittent fasting enhances cancer therapyWorld journal of clinical oncology · 2026Review
- Intermittent fasting in osteoarthritis: from mechanistic insights to therapeutic potential.Frontiers in nutrition · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Time-restricted eating is a type of intermittent fasting. Food can be consumed as desired during the eating period but not during the remainder of the day. Studies suggest that many of the health benefits of fasting may not simply be the result of weight loss but also due to the body's responses to the fasting that leads to improved metabolic functioning. Whereas animal studies are convincing regarding the benefits of time-restricted feeding, human time-restricted eating studies are less consistent and generally short term (<1 year). In 2020, the National Cancer Institute funded 5 intermittent fasting studies, 4 of which focused on time-restricted eating, which addressed the question: How does intermittent fasting affect cancer incidence, treatment response, or outcome? The National Cancer Institute sponsored a webinar in 2023 featuring investigators of the funded studies in which they discussed challenges as well as their thoughts regarding the most important time-restricted eating topics that should be addressed going forward; 6 areas were identified, which are discussed below as well as in a recently published NOT-CA-24-073: Factors Impacting How Time-Restricted Eating (TRE) Influences Cancer-Related Outcomes. Moving the science forward will allow the scientific community to better understand time-restricted eating's potential. This potential includes the development of targeted time-restricted eating interventions to optimize long-term adherence to the intervention, which is required to better understand its potential benefits in cancer risk and increased response to cancer treatment, as well as improved quality and quantity of life among cancer survivors.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.