ArticleCurrent developments in nutrition2024
Slower Pace of Epigenetic Aging and Lower Inflammatory Indicators in Females Following a Nutrient-Dense, Plant-Rich Diet Than Those in Females Following the Standard American Diet.
Article in Current developments in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Dietary pattern modifies associations between dietary factors and pace of epigenetic aging.Frontiers in nutrition · 2026Article
- Dietary approaches to support cognition in older adults: a systematic review.Frontiers in nutrition · 2026Review
- Association of the dietary inflammatory index with multi-organ biological age acceleration.Journal of health, population, and nutrition · 2025Article
- Nutritional associations with decelerated epigenetic aging: vegan diet in a Dutch population.Clinical epigenetics · 2025Article
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Authors and funding
9 authors.
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Abstract
Background: Plant-based diets are associated with lower inflammatory biomarkers and reduced risk of age-related chronic diseases. Epigenetic biomarkers of aging are DNA methylation-based tools that estimate biological age and rate of aging, providing insights into age-related health risks. Healthy diet and lifestyle indicators correlate with slower epigenetic aging. Objectives: Neither inflammatory biomarkers nor epigenetic aging has yet been studied in the nutrient-dense, plant-rich (Nutritarian) diet, a plant-based diet that emphasizes specific plant foods, such as cruciferous vegetables, beans and other legumes, onions and garlic, mushrooms, berries, nuts, and seeds. We aimed to compare inflammatory status and epigenetic age acceleration in females following a Nutritarian diet with those of females following a standard American diet (SAD). Methods: We investigated dietary inflammatory potential, epigenetic age acceleration using first, second, and third-generation clocks, and additional health-related epigenetic biomarkers in this retrospective cohort study of 48 females who habitually (≥5 y) follow a Nutritarian diet and 49 females without obesity who habitually (≥5 y) follow a SAD. Participants completed a series of online questionnaires and provided a blood sample. Results: Epigenetic age acceleration, indicated by the third-generation clock DunedinPACE, was significantly slower in the Nutritarian group than that in the SAD group ( Conclusions: Our findings suggest the Nutritarian diet could help reduce chronic inflammation and slow epigenetic aging.
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