Evidence map›Paper›PMID 39669572›Full record

ArticleFrontiers in immunology2024

Peripheral immune characteristics and subset disorder in reproductive females with endometriosis.

Kai-Rong Lin, Pei-Xian Li, Xiao-Hong Zhu, Xiao-Fan Mao, Jia-Li Peng, Xiang-Ping Chen, Cui-Yao SiTu, Li-Fang Zhang, Wei Luo, Yu-Bin Han and 1 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Decreased PD-1Scandinavian journal of immunology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Endometriosis: An Immunologist's Perspective.International journal of molecular sciences · 2025
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kai-Rong Lin *Institute of Translational Medicine, The First People'sHospital of Foshan, Foshan, Guangdong, China.
Pei-Xian Li *Institute of Translational Medicine, The First People'sHospital of Foshan, Foshan, Guangdong, China.
Xiao-Hong Zhu *Department of Gynecology, The First People's Hospital of Foshan, Foshan, Guangdong, China.
Xiao-Fan MaoInstitute of Translational Medicine, The First People'sHospital of Foshan, Foshan, Guangdong, China.
Jia-Li PengDepartment of Gynecology, The First People's Hospital of Foshan, Foshan, Guangdong, China.
Xiang-Ping ChenInstitute of Translational Medicine, The First People'sHospital of Foshan, Foshan, Guangdong, China.
Cui-Yao SiTuDepartment of Gynecology, The First People's Hospital of Foshan, Foshan, Guangdong, China.
Li-Fang ZhangInstitute of Translational Medicine, The First People'sHospital of Foshan, Foshan, Guangdong, China.
Wei LuoInstitute of Translational Medicine, The First People'sHospital of Foshan, Foshan, Guangdong, China.
Yu-Bin HanDepartment of Gynecology, The First People's Hospital of Foshan, Foshan, Guangdong, China.
Si-Fei YuInstitute of Translational Medicine, The First People'sHospital of Foshan, Foshan, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenesis of endometriosis (EN) is still unknown, but growing evidence suggests that immune regulation may be important, and the pattern of peripheral immune changes in reproductive women with EN has yet to be fully explored. In this study, we conducted a comprehensive and systematic analysis of immune cell subsets within T cells, B cells, NK cells, and γδ T cells in peripheral blood (PB) samples from women with EN, women with uterine fibroids (UF) but without EN (UF-alone), and healthy controls using multi-parameter flow cytometry. Our findings revealed that UF, a common comorbidity of EN, exhibited similar peripheral immune features to EN, particularly in T cell and B cell immunity. Compared to healthy controls, we constructed the peripheral immune profile of EN. This profile highlighted that the immunopathogenic factors in EN predominantly relate to the immune disorder of B cells and their subsets, as well as the functional abnormalities within immune cell subsets of CD4

Indexed as

B-LymphocytesEndometriosisAdultCase-Control StudiesFemaleHumansKiller Cells, NaturalLeiomyomaT-Lymphocyte Subsetsdiagnosisendometriosisflow cytometryimmune cell subsetperipheral immune profile

Identifiers

PMID39669572
PMCPMC11634862

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.