Evidence map›Paper›PMID 39669776›Full record

ArticleFrontiers in microbiology2024

Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.

Dang Li, Minghao Li, Hangqi Gao, Kailun Hu, Rongrong Xie, Jing Fan, Mingquan Huang, Chengxin Liao, Chang Han, Zhihui Guo and 2 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dang Li *Nursing Department of Fujian Medical University Union Hospital, Fuzhou, China.
Minghao Li *Department of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Hangqi Gao *Department of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Kailun Hu *Department of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Rongrong XieDepartment of Plastic Surgery, The Second Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Jing FanDepartment of Gynecology, Fuzhou Children's Hospital of Fujian Medical University, Fuzhou, China.
Mingquan HuangDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Chengxin LiaoDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Chang HanShanghai Majorbio Bio-Pharm Technology Co., Ltd., Shanghai, China.
Zhihui GuoDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Xiaosong ChenDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.
Ming LiDepartment of Plastic Surgery and Regenerative Medicine, Fujian Medical University Union Hospital, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one's quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. Owing to the poorly understood pathogenesis of keloids and their high recurrence rate, the efficacy of keloid treatment remains unsatisfactory, particularly in patients susceptible to multiple keloids. We conducted fecal metagenomic analyzes and both untargeted and targeted plasma metabolomics in patients with multiple keloids (MK,

Indexed as

gut microbiotakeloid susceptibilitymetabolitesmultiomicssingle-cell sequencing

Identifiers

PMID39669776
PMCPMC11636970

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.