Evidence map›Paper›PMID 39670213›Full record

ArticleFrontiers in dental medicine2024

Synergistic enhancement of hydrophobic dental adhesives: autonomous strengthening, polymerization kinetics, and hydrolytic resistance.

Burak Korkmaz, Erhan Demirel, Qiang Ye, Anil Misra, Candan Tamerler, Paulette Spencer

Abstract read
In one paragraph

Article in Frontiers in dental medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Burak KorkmazInstitute for Bioengineering Research, University of Kansas, Lawrence, KS, United States.
Erhan DemirelInstitute for Bioengineering Research, University of Kansas, Lawrence, KS, United States.
Qiang YeInstitute for Bioengineering Research, University of Kansas, Lawrence, KS, United States.
Anil MisraInstitute for Bioengineering Research, University of Kansas, Lawrence, KS, United States.
Candan TamerlerInstitute for Bioengineering Research, University of Kansas, Lawrence, KS, United States.
Paulette SpencerInstitute for Bioengineering Research, University of Kansas, Lawrence, KS, United States.

Funding

Peptide-Polymer Engineering Dentin/Adhesive Interfacial Bond IntegrityR01DE025476 · NIDCR · UNIVERSITY OF KANSAS LAWRENCE · PI SPENCER, PAULETTE, TAMERLER-BEHAR, CANDAN · 2015 to 2024
$3.2M
Peptide Enabled Tunable Restorative InterfaceR56DE032903 · NIDCR · UNIVERSITY OF KANSAS LAWRENCE · PI SNEAD, MALCOLM L., SPENCER, PAULETTE · 2023 to 2023
$467k
NIDCR NIH HHS R01 DE025476NIDCR NIH HHS R56 DE032903
6 · The paper itself

Abstract

The leading cause of composite restoration failure is recurrent marginal decay. The margin between the composite and tooth is initially sealed by a low-viscosity adhesive, but chemical, physical, and mechanical stresses work synergistically and simultaneously to degrade the adhesive, destroying the interfacial seal and providing an ideal environment for bacteria to proliferate. Our group has been developing self-strengthening adhesives with improved chemical and mechanical characteristics. This paper reports a self-strengthening adhesive formulation that resists hydrolysis-mediated degradation by providing intrinsic reinforcement of the polymer network through synergistic stimulation of free-radical polymerization, sol-gel reaction, and hydrophobicity. Hydrophobic resin formulation (NE1) was developed using HEMA/BisGMA 28/55w/w and 15 wt% MPS. Control (NC1) contained HEMA/BisGMA 28/55 w/w and 15 wt% MES. The polymerization kinetics, water sorption, leachates, and dynamic mechanical properties of the resin samples were investigated. The NC1 and NE1 samples showed comparable polymerization kinetics, degree of conversion and water sorption. In contrast, NC1 showed significantly higher levels of HEMA and BisGMA leachate, indicating faster degradation in ethanol. At day 3, cumulative HEMA leachate for NC1 was tenfold greater than NE1 (

Indexed as

dental adhesivedynamic mechanical analysishighly crosslinked networkhydrolytic degradationhydrophobic resinssol-gel reaction

Identifiers

PMID39670213
PMCPMC11636420

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.