Evidence map›Paper›PMID 39670465›Full record

ArticleParasitology2025

Genome-wide association study analysis of single nucleotide variants in

Amanda Miranda da Silva, Kátia Silene Sousa Carvalho, Caio Andrey Bezerra Januário, Raquel Gomes de Sena Carneiro Caldas, Bianka Lopes da Silva Paulino, Débora Cavalcante Braz, Dorcas Lamounier Costa, Gabriel da Luz Wallau, Wilson Jose da Silva Junior, Carlos Henrique Nery Costa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasitology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amanda Miranda da SilvaPostgraduate Program in Biotechnology, Northeast Network of Biotechnology, Federal University of Piauí, Piauí, Brazil.ORCID https://orcid.org/0000-0001-6476-4809
Kátia Silene Sousa CarvalhoLeishmaniasis Research Laboratory - LabLeish, Piauí, Brazil.
Caio Andrey Bezerra JanuárioPostgraduate Program in Genetics and Molecular Biology, Federal University of Pernambuco - UFPE, Pernambuco, Brazil.
Raquel Gomes de Sena Carneiro CaldasPostgraduate Program in Biological Sciences, Federal University of Pernambuco - UFPE, Pernambuco, Brazil.
Bianka Lopes da Silva PaulinoLeishmaniasis Research Laboratory - LabLeish, Piauí, Brazil.
Débora Cavalcante BrazPharmacy Course, Federal University of Piauí, Piauí, Brazil.
Dorcas Lamounier CostaPostgraduate Program in Biotechnology, Northeast Network of Biotechnology, Federal University of Piauí, Piauí, Brazil.
Gabriel da Luz WallauDepartment of Entomology, Instituto Aggeu Magalhães, Fundação Oswaldo Cruz - Fiocruz, Pernambuco, Brazil.
Wilson Jose da Silva JuniorDepartment of Entomology, Instituto Aggeu Magalhães, Fundação Oswaldo Cruz - Fiocruz, Pernambuco, Brazil.
Carlos Henrique Nery CostaPostgraduate Program in Biotechnology, Northeast Network of Biotechnology, Federal University of Piauí, Piauí, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 475102/2011-8Conselho Nacional de Desenvolvimento Científico e Tecnológico 55479712006-2
6 · The paper itself

Abstract

Elevated levels of IL-6 in plasma are associated with the severity of visceral leishmaniasis (VL). The clinical manifestations of VL vary among patients, influenced by host factors and the virulence of the

Indexed as

Interleukin-6Leishmania infantumLeishmaniasis, VisceralPolymorphism, Single NucleotideAdultBiomarkersFemaleGenome-Wide Association StudyHumansInflammationMaleMiddle AgedBiomarkersIL6 protein, humanInterleukin-6genome-wide association studygenomicsinterleukin-6Leishmania infantumvisceral leishmaniasis

Identifiers

PMID39670465
PMCPMC12644933

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.