Evidence mapPaperPMID 39672780Full record

ArticleInternational dental journal2025

Association Between High Dietary Advanced Glycation End Products and Periodontitis.

Yuehan Zhang, Jiayu Shu, Qiyang Ma, Hongli Gao, Yufeng Qin, Qiang Dong, Helin Chen

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Article in International dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yuehan ZhangDepartment of Stomatology, Guizhou Medical University, Guiyang, Guizhou Province, China.
Jiayu ShuDepartment of Stomatology, Guizhou Medical University, Guiyang, Guizhou Province, China.
Qiyang MaDepartment of Dean's Office, Affiliated Stomatological Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China.
Hongli GaoDepartment of Stomatology, Guizhou Medical University, Guiyang, Guizhou Province, China.
Yufeng QinDepartment of Stomatology, Guizhou Medical University, Guiyang, Guizhou Province, China.
Qiang DongDepartment of Prosthodontics & Implant Dentistry, Affiliated Stomatological Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China. Electronic address: 791400804@qq.com.
Helin ChenDepartment of Prosthodontics & Implant Dentistry, Affiliated Stomatological Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China. Electronic address: helinchen0509@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe study aimed to provide evidence for a relationship between a high dietary intake of advanced glycation end products, and periodontitis. MATERIALS AND

methodsA total of 2334 adults from the National Health and Nutrition Examination Survey (NHANES) during 2003-2004 were included in this study. Binary regression analysis was conducted to measure the association between periodontitis and dietary advanced glycation end products (AGEs), and two adjusted models were constructed to further explore the relationship.

resultsParticipants with AGEs intake above 21.41 U/kcal had a higher prevalence of periodontitis compared to those with lower AGEs intake. After fully adjusting for associated factors, the odds ratios for periodontitis in relation to higher AGEs intake were 1.229 (95% confidence interval 1.015-1.488, p = .034), 1.349 (95% confidence interval 1.157-1.642, p = .003), and 1.331 (95% confidence interval 1.088-1.630 p = .006), respectively.

conclusionsOur cross-sectional study reveals a strong association between periodontitis and AGEs. CLINICAL RELEVANCE: An association between advanced glycation end products in the diet and periodontitis implies the importance of the quality of food intake for good oral health. PRINCIPAL

findingsThe consumption of dietary advanced glycation end products is associated with an increased susceptibility to periodontitis development. PRACTICAL IMPLICATIONS: These findings contribute to recognizing the harm of advanced glycation end products in various foods to periodontitis, and guiding clinical oral education.

Indexed as

DietGlycation End Products, AdvancedPeriodontitisAdultAgedCross-Sectional StudiesDietary Advanced Glycation End ProductsFemaleHumansMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsDietary Advanced Glycation End ProductsGlycation End Products, Advanceddietary advanced glycation end productsNHANESoral healthPeriodontitis

Identifiers

PMID39672780
PMCPMC11976597

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.