Evidence map›Paper›PMID 39673588›Full record

ReviewNeurochemical research2024

Mechanism and Clinical Application Prospects of Mitochondrial DNA Single Nucleotide Polymorphism in Neurodegenerative Diseases.

Mengying Xu, Tianjiao Li, Xuan Liu, Binish Islam, Yuyue Xiang, Xiyan Zou, Jianwu Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurochemical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengying Xu *Xiangya School of Public Health, Central South University, Changsha, 410078, China.
Tianjiao Li *Xiangya School of Public Health, Central South University, Changsha, 410078, China.
Xuan LiuXiangya School of Public Health, Central South University, Changsha, 410078, China.
Binish IslamXiangya School of Public Health, Central South University, Changsha, 410078, China.
Yuyue XiangXiangya School of Public Health, Central South University, Changsha, 410078, China.
Xiyan ZouXiangya School of Public Health, Central South University, Changsha, 410078, China.
Jianwu WangXiangya School of Public Health, Central South University, Changsha, 410078, China. jianwu_wang@csu.edu.cn.

Funding

Natural Science Foundation of Changsha kq2202128Natural Science Foundation of Hunan Province 2022JJ40667
6 · The paper itself

Abstract

Mitochondrial dysfunction is well recognized as a critical component of the complicated pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. This review investigates the influence of mitochondrial DNA single nucleotide polymorphisms on mitochondrial function, as well as their role in the onset and progression of these neurodegenerative diseases. Furthermore, the contemporary approaches to mitochondrial regulation in these disorders are discussed. Our objective is to uncover early diagnostic targets and formulate precision medicine strategies for neurodegenerative diseases, thereby offering new paths for preventing and treating these conditions.

Indexed as

DNA, MitochondrialMitochondriaNeurodegenerative DiseasesPolymorphism, Single NucleotideAnimalsHumansDNA, MitochondrialMitochondrial dysfunctionMitochondrial regulation technologiesmtDNANeurodegenerative diseasesSNPs

Identifiers

PMID39673588

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.