Evidence mapPaperPMID 39674630Full record

ReviewJournal, genetic engineering & biotechnology2024

The positive implication of natural antioxidants on oxidative stress-mediated diabetes mellitus complications.

Shouvik Mallik, Bijoy Paria, Sayed Mohammad Firdous, Hesham S Ghazzawy, Nashi K Alqahtani, Yong He, Xiaoli Li, Mostafa M Gouda

Abstract readReview
In one paragraph

Review in Journal, genetic engineering & biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shouvik MallikDepartment of Pharmacology, Calcutta Institute of Pharmaceutical Technology & AHS, Uluberia, Howrah, West Bengal, India.
Bijoy PariaDepartment of Pharmacology, Calcutta Institute of Pharmaceutical Technology & AHS, Uluberia, Howrah, West Bengal, India.
Sayed Mohammad FirdousDepartment of Pharmacology, Calcutta Institute of Pharmaceutical Technology & AHS, Uluberia, Howrah, West Bengal, India. Electronic address: firdous.oncology@gmail.com.
Hesham S GhazzawyDate Palm Research Center of Excellence, King Faisal University, Al Ahsa, Saudi Arabia; Central Laboratory for Date Palm Research and Development, Agriculture Research Center, Giza 12511, Egypt. Electronic address: hghazzawy@kfu.edu.sa.
Nashi K AlqahtaniDate Palm Research Center of Excellence, King Faisal University, Al Ahsa, Saudi Arabia.
Yong HeCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China.
Xiaoli LiCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China. Electronic address: Xiaolili@zju.edu.cn.
Mostafa M GoudaCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou 310058, China; Department of Nutrition & Food Science, National Research Centre, Dokki, Giza 12622, Egypt. Electronic address: mostafa-gouda@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complementary intervention to modulate diabetes mellitus (DM) metabolism has recently brought the global attention, since DM has become among the global burden diseases. Where, several related pathways elevate the production of superoxide in consequences. For example, the flux of glycation-derived end products (AGEs) could lead to the deactivation of insulin signaling pathways. In that context, many vitamins and phytochemicals in natural sources have high antioxidant impacts that reduce oxidative stress and cell damages. These chemicals could be applied as bioactive antidiabetic agents. Their mode of actions could be from regulating the intracellular reactive oxygen species (ROS) which cause several pro-inflammatory pathways related to the oxidative stress (OS) and DM. Besides, they have a great potential to control the epigenetic mutations and hyperglycemia and help in back the blood glucose to the normal level. Therefore, the current review addresses the important role of natural functional antioxidants in DM management and its association with its OS complications.

Indexed as

AntioxidantsDiabetes mellitus (DM)Insulin resistanceoxidative stress (OS)

Identifiers

PMID39674630
PMCPMC11416289

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.