Evidence map›Paper›PMID 39676068›Full record

ArticleNMR in biomedicine2025

Multinuclear MRI Can Depict Metabolic and Energetic Changes in Mild Traumatic Brain Injury.

Thomas M Thorsen, Nikolaj Bøgh, Lotte B Bertelsen, Esben S S Hansen, Christoffer Laustsen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NMR in biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas M ThorsenThe MR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-5696-8975
Nikolaj BøghThe MR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Lotte B BertelsenThe MR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-2491-3184
Esben S S HansenThe MR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Christoffer LaustsenThe MR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-0317-2911

Funding

Lundbeck Foundation R272-2017-4023
6 · The paper itself

Abstract

Mild traumatic brain injuries (TBIs) are frequent in the European population. The pathophysiological changes after TBI include metabolic changes, but these are not observable using current clinical tools. We aimed to evaluate multinuclear MRI as a mean of assessing these changes. In our model, pigs were exposed to a controlled cortical impact (CCI) directly on the dura and scanned at 2 h and 2 days after injury. A multinuclear MRI protocol was used. It included hyperpolarized [1-

Indexed as

Magnetic Resonance ImagingPyruvic AcidAnimalsBrain ConcussionBrain Injuries, TraumaticCerebrovascular CirculationEnergy MetabolismFemaleLactic AcidMaleMicrodialysisSwineLactic AcidPyruvic AcidlactatemetabolismmicrodialysisMRITBI

Identifiers

PMID39676068
PMCPMC11646961

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.