Evidence map›Paper›PMID 39676794›Full record

ArticleFrontiers in cell and developmental biology2024

Brachyury co-operates with polycomb protein RYBP to regulate gastrulation and axial elongation

Lilla Kokity, Zsolt Czimmerer, Bernadett Benyhe-Kis, Anna Poscher, Emese Belai, Gábor Steinbach, Zoltan Lipinszki, Melinda Katalin Pirity

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lilla KokityBiological Research Centre, Institute of Genetics, Hungarian Research Network, Szeged, Hungary.
Zsolt CzimmererBiological Research Centre, Institute of Genetics, Hungarian Research Network, Szeged, Hungary.
Bernadett Benyhe-KisBiological Research Centre, Institute of Genetics, Hungarian Research Network, Szeged, Hungary.
Anna PoscherBiological Research Centre, Institute of Genetics, Hungarian Research Network, Szeged, Hungary.
Emese BelaiBiological Research Centre, Institute of Genetics, Hungarian Research Network, Szeged, Hungary.
Gábor SteinbachCellular Imaging Laboratory, Core Facility, Biological Research Centre, Hungarian Research Network, Szeged, Hungary.
Zoltan LipinszkiSynthetic and Systems Biology Unit, Institute of Biochemistry, Biological Research Centre, Hungarian Research Network, Szeged, Hungary.
Melinda Katalin PirityBiological Research Centre, Institute of Genetics, Hungarian Research Network, Szeged, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early embryonic development is a complex process where undifferentiated cells lose their pluripotency and start to gastrulate. During gastrulation, three germ layers form, giving rise to different cell lineages and organs. This process is regulated by transcription factors and epigenetic regulators, including non-canonical polycomb repressive complex 1s (ncPRC1s). Previously, we reported that ncPRC1-member RYBP (RING1 and YY1 binding protein) is crucial for embryonic implantation and cardiac lineage commitment in mice. However, the role of RYBP in gastrulation and mesoderm formation has not yet been defined. In this study, we used 2D and 3D

Indexed as

axial elongationgastruloidmesodermpolycomb complexRYBP

Identifiers

PMID39676794
PMCPMC11638158

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.