Evidence map›Paper›PMID 39677050›Full record

ArticleWorld journal of otorhinolaryngology - head and neck surgery2024

Epstein-Barr virus in tonsillar tissue of Iranian children with tonsillar hypertrophy: Quantitative measurement by real-time PCR.

Shirin Kalantari, Sevrin Zadheidar, Zahra Heydarifard, Ahmad Nejati, Kaveh Sadeghi, Somayeh Shatizadeh Malekshahi, Nastaran Ghavami, Talat Mokhtari-Azad, Nazanin-Zahra Shafiei-Jandaghi

Abstract read
In one paragraph

Article in World journal of otorhinolaryngology - head and neck surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shirin KalantariDepartment of Virology, School of Public Health Tehran University of Medical Sciences Tehran Iran.
Sevrin ZadheidarDepartment of Virology, School of Public Health Tehran University of Medical Sciences Tehran Iran.
Zahra HeydarifardDepartment of Virology, School of Public Health Tehran University of Medical Sciences Tehran Iran.
Ahmad NejatiDepartment of Virology, School of Public Health Tehran University of Medical Sciences Tehran Iran.
Kaveh SadeghiDepartment of Virology, School of Public Health Tehran University of Medical Sciences Tehran Iran.
Somayeh Shatizadeh MalekshahiDepartment of Virology, Faculty of Medical Sciences Tarbiat Modares University Tehran Iran.
Nastaran GhavamiDepartment of Virology, School of Public Health Tehran University of Medical Sciences Tehran Iran.
Talat Mokhtari-AzadDepartment of Virology, School of Public Health Tehran University of Medical Sciences Tehran Iran.
Nazanin-Zahra Shafiei-JandaghiDepartment of Virology, School of Public Health Tehran University of Medical Sciences Tehran Iran.ORCID 0000-0002-6988-4321

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Epstein-Barr virus (EBV) infection is ubiquitous all around the world. Tonsils seem to be candidate replication sites for EBV, and these tissues can be infected acutely or chronically. Some studies reported an association between EBV infection and tonsillar hypertrophy. In this study, we aimed to evaluate the presence and copy number of the EBV genome in tonsil tissue specimens of patients with tonsillar hypertrophy. Methods: A cross-sectional study was performed on 50 fresh tonsil tissue samples from children, who underwent tonsillectomy because of tonsillar hypertrophy. Patients' tonsil tissues were evaluated using real-time polymerase chain reaction for EBV genome and viral load. Finally, the results were analyzed using SPSS software. Results: EBV genome was detected in 58% (29/50) of tonsillar tissues. The relationship between EBV genome detection rate and age groups was in the statistical significance range ( Conclusion: Herein, EBV genome detection could support the colonization of EBV in the tonsils, which may have a direct or indirect association with the pathogenesis of tonsillar hypertrophy.

Indexed as

EBVIrantonsillar hypertrophy

Identifiers

PMID39677050
PMCPMC11634726

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.