Evidence map›Paper›PMID 39677290›Full record

ArticleJournal of inflammation research2024

Indian Shot (

Mohammad Abdullah Taher, Hasin Hasnat, Safaet Alam, Suriya Akter Shompa, Mirola Afroze, Mala Khan, Chuxiao Shao, Shuanghu Wang, Peiwu Geng, Abdullah Al Mamun

Abstract read
In one paragraph

Article in Journal of inflammation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohammad Abdullah TaherDepartment of Pharmaceutical Chemistry, University of Dhaka, Dhaka, 1000 Bangladesh.
Hasin HasnatDepartment of Pharmacy, State University of Bangladesh, Dhaka, 1207 Bangladesh.
Safaet AlamDepartment of Pharmaceutical Chemistry, University of Dhaka, Dhaka, 1000 Bangladesh.
Suriya Akter ShompaDepartment of Pharmacy, State University of Bangladesh, Dhaka, 1207 Bangladesh.
Mirola AfrozeBangladesh Reference Institute for Chemical Measurements (BRiCM), Dhaka, 1205 Bangladesh.
Mala KhanBangladesh Reference Institute for Chemical Measurements (BRiCM), Dhaka, 1205 Bangladesh.
Chuxiao ShaoCentral Laboratory of The Lishui Hospital of Wenzhou Medical University, The First Affiliated Hospital of Lishui University, Lishui People's Hospital, Lishui, Zhejiang, 323000, People's Republic of China.
Shuanghu WangCentral Laboratory of The Lishui Hospital of Wenzhou Medical University, The First Affiliated Hospital of Lishui University, Lishui People's Hospital, Lishui, Zhejiang, 323000, People's Republic of China.ORCID 0000-0002-0057-267X
Peiwu GengCentral Laboratory of The Lishui Hospital of Wenzhou Medical University, The First Affiliated Hospital of Lishui University, Lishui People's Hospital, Lishui, Zhejiang, 323000, People's Republic of China.
Abdullah Al MamunCentral Laboratory of The Lishui Hospital of Wenzhou Medical University, The First Affiliated Hospital of Lishui University, Lishui People's Hospital, Lishui, Zhejiang, 323000, People's Republic of China.ORCID 0000-0001-9936-3925

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Throughout history, plants have played a crucial role in advancing medicinal treatments by providing a diverse range of compounds for the development of innovative therapies. Objective: This comprehensive research invesigates the extract preparation of Methods: The research, an international collaboration involving researchers from Bangladesh and China, utilized GC-MS/MS analysis to identify bioactive compounds across different Results: The GC-MS/MS analysis identified 35, 43, 27, and 20 compounds in dichloromethane, aqueous, petroleum ether, and ethyl acetate extracts, respectively. The aqueous (AQSF) and dichloromethane (DCMSF) extracts showed notable antimicrobial activity, particularly against gram-negative bacteria. Cytotoxicity tests indicated that ethyl acetate (EASF) and dichloromethane (DCMSF) fractions were potent. Analgesic activity was highest in DCMSF, and antidiarrheal effects were dose-dependent, with DCMSF showing the greatest efficacy. Molecular docking revealed strong affinities of Ergostane-3,5,6,12,25-pentol, 25-acetate, (3.beta.,5.alpha.,6.beta.,12.beta).- for EGFR and Norgestrel for COX-2. Conclusion: This research provides valuable insights into the bioactivity evaluation of

Indexed as

analgesicantidiarrhealantimicrobialCanna indicacytotoxicityGC-MS/MSmolecular docking

Identifiers

PMID39677290
PMCPMC11646432

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.