Evidence map›Paper›PMID 39677300›Full record

ArticleJournal of inflammation research2024

Crescents as Independent Risk Factor in the Progression of Primary Membranous Nephropathy.

Shang-Mei Li, La-Wei Yang, Zhi-Qing Huang, Jia-Ying Ma, Jiao-Hua Wu, Hua-Feng Liu, Yong-Zhi Xu, Mian-Na Luo

Abstract read
In one paragraph

Article in Journal of inflammation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shang-Mei Li *Department of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, 524001, People's Republic of China.
La-Wei Yang *Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, 524001, People's Republic of China.
Zhi-Qing HuangDepartment of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, 524001, People's Republic of China.
Jia-Ying MaDepartment of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, 524001, People's Republic of China.
Jiao-Hua WuDepartment of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, 524001, People's Republic of China.
Hua-Feng LiuDepartment of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, 524001, People's Republic of China.
Yong-Zhi XuDepartment of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, 524001, People's Republic of China.
Mian-Na LuoDepartment of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong Province, 524001, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The role of crescent formation in primary membranous nephropathy (PMN) and its potential impact on prognosis remain an area of ongoing investigation. This study stratifies patients with PMN into two cohorts: one with crescents and one without. It then compares these groups to investigate the influence of crescents on the prognosis of PMN. Methods: In this retrospective analysis, we included patients who had a confirmed diagnosis of PMN and exhibited crescents upon renal biopsy. The study population was sourced from the medical records at the Affiliated Hospital of Guangdong Medical University in Zhanjiang, China, spanning from January 2017 to June 2023. To enable a comparative analysis of clinical, pathological, and prognostic features, a control group was established, comprising 106 patients diagnosed with PMN who did not have crescent formation. These controls were randomly selected from the same time frame. Regular follow-up of the patients continued in the outpatient setting for at least six months. Results: A total of 53 patients with PMN and crescent formation were included in this study, while 106 individuals without crescents served as a randomly selected control group. Patients with PMN and crescents exhibited higher systolic blood pressure ( Conclusion: Crescent formation is associated with a risk of adverse outcomes in patients with PMN. Patients with crescents exhibit severe clinical and pathological features and have poorer prognoses.

Indexed as

crescentsprimary membranous nephropathyrisk factor

Identifiers

PMID39677300
PMCPMC11646461

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.