Exploring the Potential and Challenges of Digital and AI-Driven Psychotherapy for ADHD, OCD, Schizophrenia, and Substance Use Disorders: A Comprehensive Narrative Review.

Purpose of the Review: Psychotherapy remains a fundamental component of mental health treatment, yet it encounters significant barriers to accessibility and efficacy. The integration of digital therapies, encompassing e-Health, m-Health, and artificial intelligence (AI) offers the transformative potential to enhance therapeutic processes through automated systems that improve access and personalize treatment. This integration, however, involves complex considerations, including health-related quality of life (HRQoL) and the dynamics of the therapeutic alliance. This narrative review synthesizes current literature on the application of digital therapies in psychotherapy, with a focus on attention-deficit/hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), schizophrenia, and substance use disorders (SUDs). The review evaluates the effectiveness of these interventions, their impact on HRQoL, therapeutic relationships, and the associated ethical considerations. Collection and Analysis of Data: Following Green's checklist for narrative reviews, a systematic literature review was conducted on studies published from January 2009 to May 2024. Inclusion criteria centered on digital therapies, including AI-based, Internet-based, and mobile-based interventions in psychotherapy. A total of 23 studies were analyzed. Conclusions: The findings indicate that digital therapies hold substantial promise for enhancing therapeutic interventions across various mental health disorders, particularly through chatbots and Internet-based psychotherapy. However, successful integration requires careful attention to the therapeutic alliance, HRQoL, and ethical implications. This review highlights the significant potential of digital therapies, including AI-driven psychotherapy, in managing diverse mental health disorders. A balanced approach to integration, prioritizing patient well-being and addressing ethical complexities, is essential for optimizing treatment outcomes.