Evidence map›Paper›PMID 39677950›Full record

ArticlePeerJ2024

Proteomic analysis of giant panda testicular tissue of different age groups.

Jing Peng, Tao Wang, Feiping Li, Shenfei Wang, Mengshi Zhang, James Ayala, Yuliang Liu, Rong Hou, Kailai Cai

Abstract read
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jing Peng *School of Pharmacy, Chengdu University, Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu, Sichuan, China.
Tao Wang *School of Pharmacy, Chengdu University, Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, Chengdu, Sichuan, China.
Feiping LiSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu, Sichuan, China.
Shenfei WangSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu, Sichuan, China.
Mengshi ZhangSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu, Sichuan, China.
James AyalaSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu, Sichuan, China.
Yuliang LiuSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu, Sichuan, China.
Rong HouSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu, Sichuan, China.
Kailai CaiSichuan Key Laboratory of Conservation Biology for Endangered Wildlife, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The reproductive ability of male giant pandas has been a major complicating factor in the Methods: Samples from the testes of three giant pandas (22 years, 18 years, 8 days) were studied to assess the protein's function. A label-free quantitative method was used to isolate testicular proteins from each male, 139,039 peptides and 11,435 proteins were obtained. Results: Gene Ontology (GO) annotates most of the proteins involved in the processes of protein phosphorylation, oxidation-reduction, proteolysis, and signal transduction. KEGG pathway indicated that most of the proteins were involved in the pathway of signal transduction, transport, and catabolism. The protein kinase and WD40 repeats were involved in protein-protein interaction, which in turn regulates gene expression in the testicular tissue of giant pandas. Conclusions: This study is the first to conduct an in-depth proteomic analysis of testicular tissue in giant pandas. The results revealed the important role of proteins in testicular tissue on spermatogenesis, testosterone production, and testicular microenvironment, providing clues for further research on male giant panda reproduction.

Indexed as

ProteomicsTestisUrsidaeAnimalsMaleSpermatogenesisGiant pandasProteomicsTesticular tissue

Identifiers

PMID39677950
PMCPMC11639135

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.