Evidence map›Paper›PMID 39678514›Full record

ArticleFrontiers in oncology2024

Exfoliative esophagitis secondary to tislelizumab: a case report.

Mingxing Wang, Qingming Sun, Wanhui Dong

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mingxing WangDepartment of Medical Oncology, Lu'an Hospital of Traditional Chinese Medicine Affiliated To Anhui University of Chinese Medicine, Lu'an, China.
Qingming SunDepartment of Medical Oncology, Lu'an Hospital of Traditional Chinese Medicine Affiliated To Anhui University of Chinese Medicine, Lu'an, China.
Wanhui DongDepartment of Medical Oncology, Lu'an Hospital of Traditional Chinese Medicine Affiliated To Anhui University of Chinese Medicine, Lu'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tislelizumab, as a PD-1 inhibitor, has demonstrated significant efficacy in cancer treatment. However, it may also induce immune-related adverse events (irAEs). This case report describes a patient who developed oral ulcers and dysphagia following treatment with tislelizumab, which was diagnosed as exfoliative esophagitis through endoscopic examination. The condition improved after corticosteroid pulse therapy. A review of the relevant literature revealed no prior reports of immune checkpoint inhibitor (ICI)-related esophagitis cases, prompting an exploration of the potential pathophysiological mechanisms and therapeutic strategies. This report emphasizes the importance of vigilance for rare irAEs during ICI therapy, advocating for early detection and timely intervention.

Indexed as

case reportexfoliative esophagitisimmune checkpoint inhibitorsimmune-related adverse eventstislelizumab

Identifiers

PMID39678514
PMCPMC11638584

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.